Page 43 - MemoriaEHD-Eng

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TRASLATIONAL AND CLINICAL RESEARCH. The main results of the clinical re-
Highlights
search activity of the group have been:

• Study of the mechanisms involved T cell dynamics in cirrhosis. We have explained

Th-cell immunodeficiency in cirrhosis by a universal defect in thymopoiesis
exacerbated by splenic pooling and activation-driven cell-death induced by

bacterial translocation.

• Systemic inflamation in a murine cirrhosis without bacterial translocation.

• Acute on chronic liver failure. Involvement in the studies leading to the clinical

characterization of ACLF and the role of extracorporeal albumin dyalisis

• Hepatocellular carcinoma and portal hypertension. Relevance of rebleedig

prevention in patients with hepatocellular carcinoma, and potential role of beta-
blockers in hepatocellualr carcinoma prevention

Master in Hepatology. Organization and development of Master in Hepatology

2012/2013, as an integrated action of the Universities of Alcalá, Autónoma de

Madrid, Universidad Complutense de Madrid, Sevilla y Cantabria, as well as CI-
BERehd.

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