Page 102 - MemoriaER-Eng

RESEARCH GROUPS

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PROGRAMME:
Group U717
Mitochondrial Medicine

Group Members
Lead Researcher

Garesse Alarcón, Rafael
STAFF MEMBERS
Gallardo Prez, Mara Esther

ASSOCIATED MEMBERS
Contact:
Instituto de Investigaciones Biomédicas “Alberto Sols” Bornstein Snchez, Beln

CSIC-UAM. Clemente Prez, Paula
Dep. de Modelos Experimentales de Enfermedades Humanas Echevarra Zamora, Luca

C/ Arzobispo Morcillo, 4. 28029 Madrid · Phone: (+34) 91 497 54 08 Fernndez Moreno, Miguel ngel
E.mail: [email protected] · Website: http://www.iib.uam.es
Galera Monge, Teresa

Garca Vallejo, Carmen
Prior De Castro, Carmen
Main lines of research
Snchez Martnez, lvaro

• Identification and characterization of new proteins involved in the regula-

tion of the OXPHOS system.

• Functional analysis by means of transmitochondrial cybrids of mutations
13
identified in the mitochondrial genome associated with LHON and neuro- 20
sensorial deafness.
T
R
• Molecular characterization of patients with intergenomic communication PO
E
defects.
L R
A
• Mitochondrial diseases with predominant phenotypic expression in cardiac NU
N
muscle: Molecular characterization and analysis by means of transmito- A
chondrial cybrids of new mutations identified in the mitochondrial genome.
/
ER
• Development of animal models of mitochondrial diseases in Drosophila ER
B
melanogaster.
CI

• Generation of iPS cells harboring mutations in structural and regulator ge-
102
nes of the OXPHOS function.