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P. 186




RESEARCH GROUPS



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PROGRAMME:
Group U761
Sensorineural Pathology





Group Members
Lead Researcher

Varela Nieto, Isabel
STAFF MEMBERS
Murillo Cuesta, Silvia 

Rodrguez De la Rosa, Lourdes 
Contact:
Vallecillo Hernndez, Nstor

CSIC, Inst. de Investigaciones Biomédicas (CSIC-UAM) 
C/ Arturo Duperier, 4. 28029 Madrid. ASSOCIATED MEMBERS
Baeza Ochoa de Ocriz, Mara Luisa 
Phone: (+34) 91 585 44 22 · E.mail: [email protected] 
http://www.ciberer.es/index.php?option=com_wrapper&Itemid=87
Cediel Algovia, Rafael 
Celaya Purtolas, Adelaida 

Contreras Rodrguez, Julio 
de Iriarte Rodrguez, Roco Main lines of research

Garca Alcntara, Fernando 
• Characterization of animal and cellular models of sensorineural hearing 
Magarios Snchez, Marta 
Martnez Vega, Raquel loss.

Pajares Tarancn, Ma ngeles - Genetics. Physiopathology of IGF-I deficit using animal and cellular 
Rivera Rodrguez, Teresa 
models. Neuroinflammatory signature and redox balance.
Rodrguez Aburto, Mara 
Snchez-Caldern, Hortensia - Environment-genome interaction in animal models of hereditary hea- 13
ring loss subjected to environmental stress: ototoxic agents, noise and 20
Sanz Lpez, Lorena T 
vitamin deficiency.
R
Zubeldia Ortuo, Jos Manuel
PO
- Associated with aging.
E
L R
• Identification of potential therapeutic targets and hearing loss progres- A
NU
sion markers. Role of the activity of pro-inflammatory kinase p38 MAPK N
in auditory damage and of the loss of function of genes from the RAF  A
 /
(RASopathy) family.
ER
ER
• Testing new therapies with small molecules and stem cells in animal B
CI
models of sensorineural hearing loss.

186
• Animal models of retinal degeneration associated with IGF-I deficit and 

intracellular targets.





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