Page 84 - MemoriaER-Eng
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RESEARCH GROUPS
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PROGRAMME:
Group U708
Endocrine Medicine
Group Members
Lead Researcher
Bernal Carrasco, Juan
STAFF MEMBERS
Morte Molina, Beatriz
Contact:
ASSOCIATED MEMBERS
Ceballos Martnez, Ainhoa
Instituto de Investigaciones Biomédicas
Contact: Beatriz Morte Gil Ibaez, Pilar
Martn Belinchn, Mnica
C/ Arturo Duperier 4. Madrid · Phone: (+34) 91 585 44 46·
E.mail: [email protected] · Website:http://www.iib.uam.es
Morreale De Castro, Gabriella
Main lines of research
• CONGENITAL HYPOTHYRODISM: Mechanisms of action of the thyroid hor-
mone in the brain. Physiopathology of neural alterations over thyroid hor-
mone deprivation during the fetal and neonatal periods. Influence of ma-
ternal thyroid hormones and consequences of maternal hypotiroxinemia
over gene expression in the fetal brain.
13
• SLC16A2 MUTATIONS: Physiopathology of the Allan-Herndon-Dudley syn- 20
T
drome and deficiency of T3 transport in the syndrome using transporter R
knock out mice. Development of new therapeutic approaches based on PO
E
thyroid hormone analogues with alternative transport.
L R
A
• THYROID HORMONE RESISTANCE: alteration mechanisms in mental re- NU
N
tardation and attention deficit- hyperactivity disorder as a consequence of A
beta type T3 receptor mutations.
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ER
ER
B
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