Page 94 - MemoriaER-Eng

RESEARCH GROUPS

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PROGRAMME:
Group U713
Mitochondrial Medicine
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íGroup Members
Lead Researcher
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STAFF MEMBERS
Cuezva, José M.

Cuevas Martn, Ma Carmen*
Nuez de Arenas Flores, Cristina

Contact:
Snchez Arag, Mara
Centro de Biologa Molecular “Severo Ochoa” (CBMSO)
ASSOCIATED MEMBERS
Universidad Autnoma de Madrid.
Departamento Dinmica y Función de Genoma. Casas Lpez, Estela
Formentini, Laura
C/ Nicols Cabrera, 1. 28048 Madrid · Phone: (+34) 91 196 46 18
E.mail: [email protected]
Garca Bermdez, Javier

Website: http://web4.cbm.uam.es/joomla-rl/index.php/es/index.php?option Martnez Jover, Estefana
=com_content&view=article&id=529
Martnez Reyes, Inmaculada

Santacatterina, Fulvio

Main lines of research

• Alterations of biogenesis and/or mitochondrial functions in human pathol-

ogy due to genetic or epigenetic causes.

• Biosynthesis, assembling and degradation of the mitochondrial oxidative 13
phosphorylation Complex V. Identification and functional characterization 20
T
of the mRNA binding proteins from the beta-F1-ATPasa subunit.
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PO
• Development of cellular and mouse models of disease with alterations in E
L R
mitochondrial oxidative phosphorylation.
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• Development of proteomic platforms for the identification of molecular N
markers of diagnosis in rare diseases related to energy metabolism.
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• Protein expression and development of monoclonal antibodies against mi- ER
tochondrial proteins and energy metabolism to be used in mitochondrial B
CI
pathologies diagnostic kits.

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* At the expense of Project