Page 121 - MemoriaES-Eng

www.ciberes.org

• As part of the actions of the Technology Transfer Platform, the Group has

developed a signal synchronization platform to be applied to biomedical

noninvasive ventilation that unifies and synchronizes the signal of respiratory
mechanics with the consequences of pulmonary gas exchange and patient effort.

• l M, B J, g M, F V, B g, P A .. Effects of immuno-
Most relevant uJánurgoSAllegoAlcóerMudolAneSet Al
compromise and comorbidities on pneumococcal serotypes causing invasive respi-
scientific ratory infection in adults: implications for vaccine strategies.Clin Infect Dis. 2013

articles
Dec;57(12):1722-30.

• SAnZ-SAntoS J, cirAuQui B, SAncHeZ e, Andreo F, SerrA P, MonSo e et Al.. Endobronchial
ultrasound-guided transbronchial needle aspiration in the diagnosis of intrathoracic

lymph node metastases from extrathoracic malignancies.Clin Exp Metastasis. 2013

Apr;30(4):521-8.

• gArcíA-nuñeZ M, Quero S, cAtini S, Pedro-Botet Ml, MAteu l, SoPenA n et Al.. Comparati-
ve molecular and antibody typing during the investigation of an outbreak of Legion-

naires’ disease.J Infect Chemother. 2013 Oct;19(5):896-901.

• Sogo A, MontAnYà J, MonSó e, BlAncH l, PoMAreS X, luJàn M. Effect of dynamic random
leaks on the monitoring accuracy of home mechanical ventilators: a bench study.

BMC Pulm Med. 2013 Dec 10;13:75.

• cuBero n, eSteBAn J, PAlenQue e, roSell A, gArcíA MJ. Evaluation of the detection of My-
cobacterium tuberculosis with metabolic activity in culture-negative human clinical

samples.Clin Microbiol Infect. 2013 Mar;19(3):273-8.

Highlights
On Lung Cancer, the Group maintains the line of diagnosis and noninvasive stag-
ing, and has consolidated the collaborative research network with SEPAR. The

Group has established a biobank of tumor lung tissue of patients with stage I and

II, and provided more than 200 samples. The program has partnered with the
International Association for the Study of Lung Cancer to incorporate molecular

staging variables, in collaboration with the Cancer RETIC. The Group has also
started a line of endoscopic navigation generating a patent (publication number

WO2013171356 A1) and the spin -off ADBRONCHUS SL.

On COPD, the Group has implemented the analysis of bronchial microbiome by

metagenomic techniques, in collaboration with Genomics and Health Area of
CSISP-FISABIO from the CIBERESP, and has demonstrated the segmentation of

the bronchial microbial composition. This line used analyzed the variability of the

respiratory microbiome in COPD, showing that the exacerbation in patients with
chronic colonization is attributable to different pathogens from colonizers.

On Pneumonia, the Group is leading a multicenter study on invasive pneumococ-
13
cal disease, and has designed an intervention project to determine the incidence 20
of nosocomial pneumonia outside the ICU. The Group collaborates with the Na- T
OR
tional Microelectronics Centre for biosensors development for Legionella detec- P
RE
tion, and environmental health studies about the effects of disinfection measures L
applied in water supplies, acting as a center of molecular typing of the Catalan A
NU
Agency for Public Health. Additionally, the group maintains the spin –off AQUALAB N
A
SL, since 2003.
S /
E
On technological innovation, the Group has developed a signal synchronization ER
platform to be applied to biomedical noninvasive ventilation that unifies and syn- B
CI
chronizes the signal mechanical respiratory signal with the consequences of gas
exchange in collaboration with Bettercare, a spin -off of Ciberes.
121