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Thirty-seven percent of the patients who were recruited present an obstructive pat-

tern, 13% present possible restrictive patterns and 27% present normal lung func-
tion. The rest (23%) are undetermined. In addition, 16% are non-smokers, 33%

are regular smokers and 40% are former smokers who quit more than 6 months
before the surgical intervention. The distribution by sex shows that the majorities

of those who are affected are men (75%), Caucasians (98%), and people between

the ages of 50-80 years old (88%). The diseases presenting the majority of co-
morbidities are COPD (stages I and II), emphysema, asthma, bronchiectasis, and

others with a history of tuberculosis and sleep apneas.

Año
Total no.
Centro hospitalario
2009 2010
2011 2012 2013
2014*
samples
Fundación Jiménez Díaz-Capio 168 257 157 1.016 57 1.655

Hospital 12 de Octubre 264 622 611 999 2.905 1.307 6.709
Hospital Clínico de Barcelona 120 385 795 950 352
4
2.606
ó
Hospital de Bellvitge
525 372 897 í
Hospital de Getafe 458 422
198 370 622 287 2.357
Hospital de Tarragona Joan XXIII 162 1.360 854 113 2.491 é

Hospital del Mar 469 932 448 913 804 243
3.809
Hospital General de Valencia 296 219
223 306
1.044
í
Hospital Germans Trias i Pujol 860 474 106 1.440
Hospital Son Espases 2.019 2.659
1.946 2.635 2.704
1.700
13.663
Proyecto GRIPE
500 500

No Muestras Totales
4.319 5.868
5.040 9.409 8.772
3.760
37.171

Table 2. Number of total samples recorded in the PBC every year in each of the participating hospitals. *2014 is incomplete
because it corresponds to data recorded at the time this report was being prepared.

The collected samples in the PBC are for the most part lung tissue (Tables 3-7) and

peripheral blood derivatives (Tables 8-11), although the management and organi-
zation for collecting another type of samples demanded by the investigators (Table

12) was implemented at the end of 2013. In the following tables the total number of
samples recorded annually according to type in each of the hospitals (Table 3-12),

and described according to the type of preservation, in the case of lung tissue ac-

cording to later applications (Table 3-7).

Year No samples
Hospital Centre
2009 2010
2011 2012 2013 2014*
(RNAlater)

Fundacin Jimnez Daz-CAPIO 6 7 5 21 1 40
Hospital 12 de Octubre 34 87 76 66 28 11 302
Hospital Clnico de Barcelona 8 27 41 41 15 1
133

Hospital de Bellvitge
28 19 47
Hospital de Getafe 18 17
8 16 20 13
92

Hospital de Tarragona Joan XXIII 4 52 36 6 98 13
Hospital del Mar 19 29 18 37 29 9 141 20
Hospital General de Valencia 36 28
26 28
118 T
OR
Hospital Germans Trias i Pujol 28 17 3 48 P
Hospital Son Espases
74 72 56 99 95 40 436
RE
L
Total no. tissue samples (RNAlater)
223 286
234 388 241 83
1.455
A
NU
Table 3. Number of samples of lung tissue conserved in RNAlater recorded annually in the PBC in each of the participating hos- N
A
pitals. *2014 is incomplete because it corresponds to data recorded at the time this report was being prepared.
S /
E
ER
B
CI

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