Page 59 - MemoriaSAM-Eng

www.cibersam.es

IDIBAPS (PI: Analía Bortolozzi) and CSIC (PI: Francesc Artigas) and at the
(02)- Artigas Pérez, request of and in collaboration with nLife Therapeutics: “Modulation of genes
Francesc
associated with the serotonergic system with antisense RNA molecules (siRNAs)
and the effect thereof on models of depression”

(18)- Micó Segura, Effect of tapentadol on Locus Coeruleus neurons “in vivo” in the streptozotocin
Juan Antonio
model of polyneuropathic pain in rats. OT2011/161

This Master Collaboration Agreement (“Agreement”) shall serve as a framework,
setting out the general terms and conditions under which the CIBERSAM shall
perform and supervise certain research projects in collaboration with Lundbeck

(02)- Artigas Pérez, (“Research Projects”). The Research Projects shall be proposed by and pre-pared
Francesc
in cooperation with Lundbeck and agreed to by the CIBERSAM from time to time.
The Research Projects shall be based on the CIBERSAM’s existing expertise,
facilities and know-how pertinent to the subject of each Research Pro-ject.
The CIBERSAM is willing to conduct the Research Projects in co-operation with
Lundbeck.
éé

Part 1- The objective of this study is to look the pattern of antidepressant intake
before and at/after baseline, how many patients took any antidepressant, how

many types of antidepressants and which ones, and compare the outcomes at
3 months between the groups of antidepressants. Part 2- To study the effect of
having co-morbidities in the relation of Somatic Symptoms and the outcomes é
(11)- Haro Abad, (depression improvement, quality of life): Is pain explained by the presence
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of diagnosed co-morbidities? Is the impact of pain on outcomes dependant on
presenting co-morbidities? Part 3- Study the relation of persistent pain with

depression severity and quality of life. Specific objectives: What happens to
patients who have persistent pain? May they improve on depression? What
happens to patients that improve on depression but not on pain? Do they have
worse quality of life?

(26)- Crespo CONTINUOUS TRAINING PROGRAMME IN EVIDENCE-BASED PSYCHOTHERAPY.
Module II: Grief and trauma from a Comprehensive Perspective (October 2012-
Facorro, Benedicto
June 2013)

(02)- Artigas Prez, Study of gene silencing in aminergic neurons with conjugated oligonucleotides
Francesc
belonging to NLIFE and MERCK SHARP DOHME (MSD)

(26)- Crespo CONTINUOUS TRAINING PROGRAMME IN EVIDENCE-BASED PSYCHOTHERAPY.
Module III: Introduction to Group Therapy from a Comprehensive Perspective
Facorro, Benedicto
(September 2013-June 2014)

1. To determine the progression of functional adaptation and cognitive
dysfunctions in a sample of euthymic bipolar patients (before and after
intervention) compared to the control group.

2. To investigate the relationship between neurotrophic changes and cognitive
deterioration and the association thereof with functional deterioration.
3. To study if this functional rehabilitation method has a beneficial effect on
(25)- Vieta Pascual, the clinical course of the disease (relapses, hospitalizations...) and long-term
Eduard
functioning (2 years of follow-up).

4. To determine the various clinical markers, biological markers (BDNF), functional
assessment (FAST) and the neurocognitive factors capable of moderating or
predicting the response to functional rehabilitation as a complementary treatment
in euthymic bipolar patients.
5. To characterize early and advanced stages according to clinical, biological and
functional variables.

(25)- Vieta Pascual,
Eduard
Translation of DSM-5 to Spanish and review
13
(03)- Ayuso Mateos, A Roadmap for Mental Health Research in Europe (ROAMER): Creating a roadmap 0
2
Jos Luis
for the priority lines of mental health research in Europe
RT
A Roadmap for Research on Mental Health and Well-being in Europe: ROAMER: PO
(03)- Ayuso Mateos, E
Jos Luis
Determining the priority lines of research in mental health and well-being in R
Europe, emphasizing Spain.
AL
(11)- Haro Abad, A Roadmap for Mental Health Research in Europe (ROAMER): Creating a roadmap U
NN
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for the priority lines of mental health research in Europe
A
A roadmap for Research on Mental Health and Well-being in Europe: ROAMER. /
(11)- Haro Abad, M
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Determining the priority lines of mental health and well-being research in Europe, SA
emphasizing Spain.
ER
(11)- Haro Abad, B
Impact of Anxiety symptoms and PPS length of stay
CI
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59
(11)- Haro Abad, Medication costs and presence of Painful Physical Symptoms and Anxiety
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Symptoms