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• P r, P n, C r, M g, r g, g-r C .. Brain effects of
Most relevant enAdéSuJolATAlánASSAnAAMeTTiArCíAizoeT Al
cognitive remediation therapy in schizophrenia: a structural and functional neuroima-
scientific
ging study.Biol Psychiatry. 2013 May 15;73(10):1015-23.
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• Bioque M, gArCíA-Bueno B, MACdowell KS, MeSeguer A, SAiz PA, PArellAdA M eT Al.. Peripheral
Endocannabinoid System Dysregulation in First-Episode Psychosis.Neuropsychopharma-

cology. 2013 Jul 4;.

• gArCíA-rizo C, Fernández-egeA e, Miller BJ, oliVeirA C, JuSTiCiA A, griFFiTh JK eT Al.. Abnor-
mal glucose tolerance, white blood cell count, and telomere length in newly diagnosed,

antidepressant-naïve patients with depression.Brain Behav Immun. 2013 Feb;28:49-53.

• BernArdo M, Bioque M, PArellAdA M, SAiz ruiz J, CueSTA MJ, llerenA A eT Al.. Assessing clini-
cal and functional outcomes in a gene-environment interaction study in first episode of

psychosis (PEPs).Rev Psiquiatr Salud Ment. 2013;6(1):4-16.

• gArCíA-Bueno B, Bioque M, MAC-dowell KS, BArConeS MF, MArTínez-CengoTiTABengoA M, PinA-

CAMACho l eT Al.. Pro-/Anti-inflammatory Dysregulation in Patients With First Episode of
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Bull. 2013 Mar 13;.
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Highlights
Schizophrenia Clinic Unit responds to both hospital care clinical approach , researcher and
teacher as an outpatient, including treatment protocols, aimed at responding to problems

posed by schizophrenia and integrates the various devices of the Hospital Clinic of Barcelona
with activity against this disease.

The objectives of the Unit are: the extension of theoretical and practical knowledge related í

to schizophrenia; longitudinal follow-up of patients with chronic schizophrenia; longitudinal
follow-up of patients with first psychotic episodes; pharmacological management of patients

with first episode of comorbid patient and patient resistant; the development and validation
of psychopathological scales; and integration into routine care, teaching or research Unit.

Our unit received in 2011 Best in Class Award for Best Unit Schizophrenia National Health

Service.
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INTERNATIONAL PROJECTS:
• Diabetes in neuropsychiatric disorders (USA)

• European Network of National schizophrenia Networks studying Gene-environment In-
teractions (EU-GEI)

• Optimization of Treatment and Manajement of Schizophrenia in Europe- OPTiMiSE
ó
• PSYSCAN – Translating neuroimaging findings from research into clinical practice.
PRINCIPAL NATIONAL PROJECTS (ISCIII):

• Genotype-phenotype and environment. Application to a predictive model in first psycho-
è
tic episodes.
à
• Determining clinical and neurobiological seconds episodes in schizophrenia. Longitudinal

study of first psychotic episodes.
• Apoptosis and progressive structural changes in patients with a first episode of schizo-
í13
phrenia: Longitudinal and multimodal neuroimaging and molecular biology 0
• BDNF (Brain-derived neurotrophic factor) as a potential biomarker of treatment of neu-
2
RT
rocognitive rehabilitation in schizophrenia negative dominance. PO
PATENT:
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R
Method for predicting the onset of extrapyramidal symptoms (EPS) induced by an antipsi- AL
chotic-based treatment. Mas, S, Gass P, Malagelada C, Bernardo M, Lafuente A
U
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CLINICAL GUIDES: A
à /
• Pla director de salut mental i addiccions.Guia de bona prctica clnica sobre la terpia
M
electroconvulsiva a Catalunya. Barcelona: Direcci General de Planificaci i Recerca en
SA
ER
Salut, Generalitat de Catalunya; 2013. B
• Bernardo M., Safont G., Oliveira C., Valiente A. Recomanacions per al monitoratge i la
CI

promoci de la salut fsica dels pacients amb esquizofrnia i altres trastorns greus. Pla 69

director de salut mental i addiccions. Departament de Salut. 2013