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CIBERDEM EUROPEAN PROJECTS
Medigene Study
EUROPEAN PROJECT
Status: Development
Website: http://www.medigene-fp7.eu/
The MEDIGENE Study is a study on the genetic and environmental factors influencing insulin resistance syndrome in Mediterranean immigrant populations . It is a 4-year collaborative project between CIBERDEM and other European institutions . It is subsidized by the European Commission under its FP7-Health-2011-
two-stage framework programme with project number 279171 and coordinated by Dr . Florin Grigorescu of the Universitè Montpellier I, France .
The project began in the year 2012 and will be concluded at the end of 2015 . The total budget for the 4-year project is 371,644 .00€ distributed as follows:
Cost distribution
The principal investigator of the project in CIBERDEM is Dr . Ramon Gomis, and his group is involved in several work packages and has several deliverables throughout its participation . There will be a very significant contribution in the project by the CIBERDEM Biobank and by other groups of the consortium such as the group of Dr . Luis Castaño .
In 2014, work has begun on WP5 “Epidemiological studies in immigrant population in host countries and obtaining new DNA samples” and work continued to be done on WP2 “Ancient DNA Studies in Tarragona” of the project .
The work on WP5 consisted of contacting different healthcare centres to identify the different immigrant communities from Morocco, Tunisia and Romania which can participate in the study . A team formed by a dietician (Mariona Balfegó) and an endocrinologist (Gloria Aranda) was sent for carrying out medical visit and nutritional survey so that they can then extract blood samples and thus obtain the DNA which has been processed by CIBERDEM researchers (Hugo Alves and Laura Brugnara) . In 2014, about 140 samples were obtained and the study is expected to be continued in 2015 .
The work of CIBERDEM on WP2 had continued to a lesser extent in 2014 and consisted of determining the genetics of ancient Roman populations in Tarragona and comparing it to modern populations of Catalonia and Italy as evidence of historical migrations and determining the prevalence of allelic variants . Various archaeological remains, primarily teeth, have been identified in collaboration with the Institut Català d’Arqueologia Clàssica (ICAC) of Tarragona, for obtaining ancient DNA samples . The extraction and amplification of DNA from dental samples have concluded in 2014 .
EU (75%)
CIBERDEM (25%)
PROJECT TOTAL
STAFF
78 .386,25 €
26 .128,75 €
104 .515,00 €
DIRECT COSTS
95 .821,87 €
31 .940,62 €
127 .762,50 €
INDIRECT COSTS
104 .524,87 €
34 .841,62 €
139 .366,50 €
TOTAL
278 .733,00 €
92 .911,00 €
371 .644,00 €
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