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INTRODUCTION
The Centro de Investigación Biomédica en Red (CIBER) is a consortium depending on Instituto de Salud Carlos III (Ministry of Economy and Competitiveness) . CIBERDEM, CIBER de Diabetes y Enfermedades Metabólicas Asociadas (Diabetes and Associated Metabolic disorders) is formed by 30 research groups located in different hospitals, universities and research centres throughout Spain .
CIBERDEM’s primary objective is to promote research on diabetes and associated metabolic disorders by identifying the genes making one more inclined to suffer said diseases and disorders and the environmental factors contributing to their development, to clarify the molecular mechanisms involved in the impairment of insulin secretion and signaling; to determine the molecular and cellular mechanisms of pancreatic beta cell formation and destruction; to study strategies for replacing said cell mass; and to conduct research on the signals linking obesity and diabetes . Research on the complications of diabetes and associated metabolic
disorders is also of special interest .
To meet its objectives, CIBERDEM seeks to generate an attractive framework for the incorporation of basic and clinical research staff, as well as the development of biomedical platforms suitable for conducting research of excellence in diabetes and associated metabolic disorders . In turn, CIBERDEM promotes translational research, favoring the transfer of acquired diabetes knowledge to other disciplines, and vice versa .
CIBERDEM’s mission is to lead the research effort of excellence in diabetes and associated metabolic disorders, and to speed up the translation of scientific results to clinical practice .
CIBERDEM conducted research activities relating to the following fields:
• Type 1 Diabetes Mellitus. Autoimmunity. • Type 2 Diabetes Mellitus. Insulin signaling and resistance. • Genetics of Diabetes Mellitus. • Diabetes Mellitus. Microvascular complications. • Dyslipidemia, inflammation and endothelial dysfunction. • Pancreatic islet dysfunction, destruction and regeneration. • Diabetes and Obesity. Biological interferences between tissues. • Diabetes and associated metabolic disorders. Glucotoxicity and lipotoxicity. • Metabolic syndrome. Physiopathology and epidemiology.
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CIBERDEM » Annual report 2014
