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RESEARCH GROUPS
Group U745
Programme: Hereditary Cancer and Related Syndromes
Lead Researcher: Surrallés, Jordi Group Members
STAFF MEMBERS: Bogliolo, Massimo | Pujol Calvet, Ma Roser | Ramirez de Haro, María José .
ASSOCIATED MEMBERS: Cabre Fabre, Oriol | Castella Castella, Maria | Hernández Viedma, Gonzalo | Marín Vilar, María | Mina, Leonardo | Minguillón Pedreño, Jordi | Montanuy Escribano, Helena | Umbert Mestres, Gloria
Main lines of research
• Genetics and molecular biology of Fanconi Anemia . Genetic characterization of Fanconi patients and identification of new genes involved in the disease and into hereditary breast cancer syndrome and its functions .
• Development of new diagnostic and therapeutic tools on Fanconi anemia, including gene therapy, regenerative medicine and drug reporsuping .
• Mechanism of genomic instability and predisposition to cancer . Study of DNA lesions repair and bio- logical and clinical consequences of repair mechanisms failure .
• Fanconi/BRCA pathway in cancer . Implication of Fanconi genes in cancer and use of them as a thera- peutic target against cancer
150 CIBERER » Annual report 2014
