Page 78 - MEMOCiberer014-ENG
P. 78
RESEARCH GROUPS
Group U708
Programme: Endocrine Medicine
Lead Researcher: Bernal, Juan Group Members
STAFF MEMBERS: Morte Molina, Beatriz ASSOCIATED MEMBERS: Gil Ibáñez, Pilar | Guadaño Ferraz, Ana Cristina | Martn Belinchon, Mónica
Main lines of research
• CONGENITAL HYPOTHYRODISM: Mechanisms of action of the thyroid hormone in the brain . Phy- siopathology of neural alterations over thyroid hormone deprivation during the fetal and neonatal periods . Influence of maternal thyroid hormones and consequences of maternal hypotiroxinemia over gene expression in the fetal brain .
• SLC16A2 MUTATIONS: Physiopathology of the Allan-Herndon-Dudley syndrome and deficiency of T3 transport in the syndrome using transporter knock out mice . Development of new therapeutic approaches based on thyroid hormone analogues with alternative transport .
• THYROID HORMONE RESISTANCE: alteration mechanisms in mental retardation and attention deficit- hyperactivity disorder as a consequence of beta type T3 receptor mutations .
78
CIBERER » Annual report 2014
