Page 88 - MEMOCiberer014-ENG
P. 88
RESEARCH GROUPS
Group U713
Programme: Mitochondrial and Neuromuscular Medicine
Lead Researcher: Cuezva, José M. Group Members
STAFF MEMBERS: Núñez de Arenas Flores, Cristina | Sánchez Arago, María AT THE EXPENSE OF THE PROJECT: Cueva Martín, Ma del Carmen
ASSOCIATED MEMBERS: Formentini, Laura | García Bermúdez, Javier | Martínez Jover, Estefanía | Martínez Reyes, Inmaculada | Santacatterina, Fulvio
Main lines of research
• Alterations of biogenesis and/or mitochondrial functions in human pathology due to genetic or epi- genetic causes .
• Biosynthesis, assembling and degradation of the mitochondrial oxidative phosphorylation Complex V . Identification and functional characterization of the mRNA binding proteins from the beta-F1-ATPasa subunit .
• Development of cellular and mouse models of disease with alterations in mitochondrial oxidative phosphorylation .
• Development of proteomic platforms for the identification of molecular markers of diagnosis on rare diseases related to energy metabolism .
• Protein expression and development of monoclonal antibodies against mitochondrial proteins and energy metabolism to be used in mitochondrial pathologies diagnostic kits .
88
CIBERER » Annual report 2014
