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RESEARCH GROUPS
Group 29
Programme: Acute Lung Injury (ALI)
Lead Researcher: Villar Hernández, Jesús Group members
STAFF MEMBERS: Cabrera Benítez, Nuria Esther | Ramos Nuez, Angela María .
ASSOCIATED MEMBERS: Acosta Herrera, Marialbert | Blanco Varela, Jesús | Corrales Moreno, Almudena | Del Pino Yanes, María del Mar | Flores Infante, Carlos Alberto | Pérez Méndez, Lina Inmaculada | Valladares Parrilla, Francisco
Main lines of research
• Epidemiology and Stratification of the Acute Respiratory Distress Syndrome (ARDS) . • Genetic Susceptibility to the Acute Respiratory Distress Syndrome . • Ventilator-Induced Lung Injury (VILI) . • Cellular and Molecular Mechanisms of Lung Repair .
• Searching from common genetic activation and signalling pathways among ARDS, Asthma and Pul- monary Fibrosis .
Most relevant scientific articles
• VILLar J, caBrera-BeNítez Ne, raMoS-Nuez a, FLoreS c, García-herNáNdez S, VaLLadareS F et al . Early ac- tivation of pro-fibrotic WNT5A in sepsis-induced acute lung injury .Critical care (London, England) . 2014;18(5):568 .
• rodrIGuez-GoNzaLez r., MartIN-BarraSa J.L., raMoS-Nuez a., caNaS-pedroSa a.M., MartINez-SaaVedra M.t., GarcIa-BeLLo M.a. et al . Multiple system organ response induced by Hyperoxia in a clinically relevant animal model of sepsis . Shock . 2014;42(2):148-153 .
• caBrera-BeNItez N.e., LaFFeY J.G., parotto M., SpIeth p.M., VILLar J., zhaNG h. et al . Mechanical ventilation- associated lung fibrosis in acute respiratory distress syndrome: A significant contributor to poor outco- me . Anesthesiology . 2014;121(1):189-198 .
• teJera p., o’MahoNY d.S., oWeN c.a., WeI Y., WaNG z., Gupta k. et al . Functional characterization of polymorphisms in the peptidase inhibitor 3 (Elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome . American Journal of Respiratory Cell and Molecular Biology . 2014;51(2):262-272 .
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