Page 118 - MEMOCiberes014-ENG

RESEARCH GROUPS
Group 31
Programme: COPD
Lead Researcher: Ruiz-Cabello Osuna, Jesús Group members
STAFF MEMBERS: Pérez Medina, Carlos | Pérez Sánchez, José Manuel ASSOCIATED MEMBERS: Benito Vicente, Marina | Bilbao Luri, Izaskun | Herranz Rabanal, Fernando | Pellico
Saez, Juan | Rodríguez Ramírez de Arellano, Ignacio | Villa Valverde, Palmira
Main lines of research
The group is integrated in the Advanced Imaging Unit (AIU) that was established in the Spanish National Centre for Cardiovascular Imaging in early 2012 . It is a multidisciplinary group focused in developing new imaging applications and molecular imaging developments that will expand the molecular and cellular knowledge of the different cardiovascular and pulmonary diseases . With this aim our research is focused on 1) Cardiovascular and Pulmonary Imaging 2) Nanomedicine and radiochemistry and 3) Metabolomics . The group offers the scientific community state of the art imaging technologies including five modalities: MRI, X-ray CT, nuclear imaging (PET), ultrasound (echocardiography) and optical (bi and tri-dimensional luminescence and fluorescence) . In the field of Nanomedicine the group encompasses a nanotechnology and organic chemistry laboratory in which we develop new nanoparticles, molecular probes and biofunctionalization techniques for the diagnosis and treatment of different cardiovascular and pulmonary diseases . Currently our group produces multifunctional nanoparticles for all imaging techniques available at our institution, like Iron Oxide, liposomes, Up-converting Nanophosphors and Gold Nanoparticles, all of them functionalized with different cardiovascular and pulmonary biomarkers . Additionally, a new 68Ga (and from beginning of 2014) 89Zr radiochemistry laboratory is fully operative to provide specific PET radiotracers for nuclear imaging . Finally, the group also has a long experience in the application of metabolic analysis to the study of different pathologies, by the use of Magnetic Resonance Spectroscopy and Mass Spectrometry and different statistical tools developed within the group . Our research projects range from technical developments and chemistry advances to in vitro studies and tracking biological processes in vivo .
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