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Aims and objectives
In our project we will focus our interests on the following problems:
• Mechanisms underlying genesis and evolution of asthma .
• Characterization of asthma phenotypes
• Characterization of asthma severity and identification of the factors that are involved in asthma severity .
• New therapies for asthma . • To identify novel biomarkers and pathways that can be translated into targets for therapeutic
strategies .
• To generate and disseminate expertise and knowledge obtained from the consortium to transfer information to scientific community and society .
Main results until the end of 2014
CLINICAL GUIDELINES:
• Bousquet J, Schünemann HJ, Samolinski B, et al . World Health Organization Collaborating Center for Asthma and Rhinitis . Allergic Rhi- nitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs . J Allergy Clin Immunol . 2012 Nov;130(5):1049-62 .
• Montoro J, Del Cuvillo A, Mullol J, Molina X, Bartra J, Dávila I, Ferrer M, Jáuregui I, Sastre J, Valero A . Validation of the modified allergic rhinitis and its impact on asthma (ARIA) severity classification in allergic rhinitis children: the PEDRIAL study . Allergy . 2012 Nov;67(11):1437-42 .
• Barranco P, Pérez-Francés C, Quirce S, Gómez-Torrijos E, Cárdenas R, Sánchez-García S, Rodríguez- Fernández F, Campo P, Olaguibel JM, Delgado J; Consensus document on the diagnosis of severe uncontrolled asthma . Severe Asthma Working Group of the SEAIC Asthma Committee . J Investig Allergol Clin Immunol . 2012; 22:460-75 .
• Moscato G, Pala G, Barnig C, De Blay F, Del Giacco SR, Folletti I, Heffler E, Maestrelli P, Pauli G, Perfetti L, Quirce S, Sastre J, Siracusa A, Walusiak-Skorupa J, van Wjik RG . EAACI consensus statement for investigation of work-rela- ted asthma in non- specialized centres . Allergy . 2012 Apr;67(4):491-501 .
• Van Kampen V, de Biay F, Folletti i, et all . EAACI position paper: skin prick testing in the diagnosis of occupational type I allergies . Allergy . Mayo de 2013;68(5):580-4 .
• Siracusa A, de Biay F, Folletti i, et all . Asthma and exposure to cleaning products - a European Academy of Allergy and Clinical Immunology task force consensus statement . Allergy . Diciembre de 2013;68(12):1532-45 .
• Canonica GW, Ansotegui iJ, Pawannkar R, et all . A WAO - ARIA - GA2LEN consensus document on molecular-based allergy diagnostics . World Allergy Organ J . 3 de octubre de 2013;6(1):17 .
PATENT:
• ENGINEERED STEM CELLS AND THEIR THERA- PEUTIC USE Inventores: Josep Maria Aran, Itziar Martínez, María Jesús Cruz, Xavier Muñoz, Joan Ramón Masclans, Oriol Roca . No de solicitud: EP11382362 .9 Entidades titulares: IDIBELL / Institut de Recerca Vall d’Hebron / CIBER Enfermedades Respiratorias (CIBERES) . País de prioridad: España Fecha de prioridad: 24 de Noviembre de 2011 Países a los que se ha extendido: Europa Empresa/s que la están explotando: Histocell .
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