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CIBERES » Annual report 2014
• In relation to this aspect, four patents have been generated (P200302551, P200602754, PCT/ ES/2002/000381; PCT/ES/2007/070081) and the creation of two compagnies has been aided for the purpose of being able to market these vaccines .
• Other relevant achievements of the Programme to be highlighted according to the directives of the “Global Plan to Stop Tuberculosis 2006-2015” include the following:
– Contribution of new knowledge about the intrinsic resistance mechanisms of M. tuberculosis, particularly in relation to “efflux pumps” .
– Development of new M. tuberculosis molecular typing techniques which allow faster and more efficient genotyping for epidemiological purposes .
– Development of new experimental animal models to measure the virulence of M. tuberculosis strains that have led to papers written through the collaboration of several groups in the Programme .
– Relevant contributions have also been made in the evaluation of new immunological techniques in the diagnosis of latent tuberculosis infection which have generated joint publications with different groups of CIBERES and other international groups . As a result of this work, several researchers of the Tuberculosis CRP have had very active participation active in drawing up clinical guidelines for the use of these new diagnostic tests for latent tuberculosis infection .
– The inter-group collaboration work within the tuberculosis programme, in collaboration with CIBERES, has generated a prominent transfer action (new M. tuberculosis molecular typing methodology) which has been worked on to generate a new patent .