Page 50 - MEMOCiberes014-ENG

PULMONARY BIOBANK CONSORTIUM
Scientific Director: Dr. Germán Peces-Barba Coordinator: Cristina Villena, PhD
Objectives
The general objectives of the Pulmonary Biobank Consortium (PBC) according to its 2012-2017 Strategic Plan approved by the PBP Steering Committee on 28 June 2012 are:
1 . RESEARCH: to cover the needs of researchers with PBP resources to promote translational research in respiratory pathologies .
2 . QUALITY: To consolidate the quality in pre- and post- sample acquisition processes to minimise artefacts and variations between batches of samples .
3 . COOPERATION: To collaborate and integrate the PBC with similar cooperative structures . 2014 Actions
To reach these objectives the following action lines were addressed in 2014:
INVENTORY ADAPTATION
Currently, samples and data have been registered from about 1,700 patients with an average of 320 cases per year, as seen in Figure 1 . Since 2013 because of budget limitations, the incorporation of new cases has been restricted to those that comply with a series of strategic requirements .
No . of enrolled cases
No . of cases that gave samples
500 400 300 200 100
0
408
328 237 226 237
321
279
163
103
0
40
30
2009 2010 2011
2012 2013 2014
Figure 1. Number of patients enlisted annually (black) and number of cases for which samples have been sent for applications requesting favourably resolved samples
After periodic analyses of the existing inventory, resources to obtain strategic and/or highly demanded samples have continued to be enhanced and focused . This is the case of healthy lungs coming from organ donors, highly diseased or difficult to access lungs coming from pulmonary explants, and other respiratory samples such as last stages of diseases, bronchoalveolar lavage, sputum, etc .
In this line a new hospital centre has been added to the PBC (Hospital Universitario Vall d’Hebron) with a high number of pulmonary transplants per year, for the incorporation of a higher number of explanted lungs . The collaboration agreement between entities was signed and equipment and formation were provided for this new centre .
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