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• The high-stretch ventilation impact in the alveolar space and in particular on the composition, structu- re, and functional activity of lung surfactant (CRP on Acute Lung Injury) .
• Benefits of intratracheal treatment of natural and synthetic surfactants as well as anti-inflammatory agents in acute lung injury induced by mechanical ventilation (CRP on Acute Lung Injury) .
This research has direct relevance for the development of new therapies for inflammatory and infectious lung diseases .
Most relevant scientific articles
• IzquIerdo-GarcIa J.L., Naz S., NIN N., roJaS Y., erazo M., MartINez-caro L. et aL. A metabolomic approach to the pathogenesis of ventilator-induced lung injury . Anesthesiology . 2014;120(3):694-702 .
• MartíNez-FLoreNSa M., coNSueGra-FerNáNdez M., MartíNez V.G., caNadaS o., arMIGer-BorraS N., BoNet-roSe- LLo L. et al . Targeting of key pathogenic factors from gram-positive bacteria by the soluble ectodomain of the scavenger-like lymphocyte receptor CD6 . Journal of Infectious Diseases . 2014;209(7):1077- 1086 .
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