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Most relevant scientific articles
• FaNer r., GoNzaLez N., cruz t., kaLko S.G., aGuStI a. . Systemic inflammatory response to smoking in chronic obstructive pulmonary disease: Evidence of a gender effect . PLoS ONE . 2014;9(5):- .
• GroSdIdIer S., Ferrer a., FaNer r., pINero J., roca J., coSIo B. et al . Network medicine analysis of COPD multimorbidities . Respiratory Research . 2014;15(1):- .
• McdoNaLd M.-L.N., cho M.h., SorheIM I.-c., Lutz S.M., caStaLdI p.J., LoMaS d.a. et aL. Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease . American Jour- nal of Respiratory Cell and Molecular Biology . 2014;51(5):678-687 .
• dIez d., aGuStI a., WheeLock c.e. . Network analysis in the investigation of chronic respiratory diseases . From basics to application . American journal of respiratory and critical care medicine . 2014;190(9):981- 988 .
• VeStBo J, aGuStI a, WouterS eF, Bakke p, caLVerLeY pM, ceLLI B et aL. Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team .American journal of respiratory and critical care medicine . 2014;189(9):1022-30 .
Highlights
Institution: Fundación de Investigación Sanitaria de las Islas Baleares Ramon Llull (FISIB) Contact: Tel .: (+34) 93 227 17 01 · E .mail: alvar .agusti@clinic .ub .es · Website: www .isciii .es
During 2014 the group 10 of CIBERES has achieved the following results:
• systems biology has been applied to COPD in order to describe the molecular networks that are com- mon to the frequent COPD comorbidities .
• we have descried that the systemic inflammatory response to smoke is different in patients with COPD than in normal lung function smokers and that it also varies according to the gender .
• the group has been involved in the COPD associated biomarker discovery and phenotyping in the context of the ECLIPSE study .
On reference to new projects, the group has initiated a study funded by the SEPAR (PI065/2013) whose PI is Alvar Agusti . The group is involved in the projects of the COPD PCI and during this year the active projects funded by ISCiii, Recercaixa, SEPAR and FUCAP have been developed as initially planned .
On reference to clinical guidelines, the group leader Dr . Agusti is member of the GOLD board (Global Initiative for Chronic Obstructive Lung Disease) that in year 2014 published the Clinical Guidelines for the Asthma, COPD and Asthma – COPD Overlap Syndrome (ACOS)(http://www .goldcopd .org/) .
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