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Research Groups
Group U718
Programme: Sensorineural Pathology Lead Researcher: González Duarte, Roser
Group members
STAFF MEMBERS: Andrés Ventura, Maria Rosa.
ASSOCIATED MEMBERS: De Castro Miró, Marta | Marfany Nadal, Gemma | Sava, Florentina.
Main lines of research
• Study of the genetic and molecular basis for in- herited retinal dystrophies (IRD).
• GeneticdiagnosisbyWESandtargetedsequenc- ing of the genes responsible for hereditary retinal dystrophies.
• Searchfornewgenescausingretinaldystrophies and functional studies.
• Functional analysis of CERKL and other relevant IRD causative genes by generating cell lines and animal models constructed by morpholino knock- down in zebrafish as well as Cerkl -/- knockout by Cre/LoxP and CRISPR/Cas-genome editing ap- proaches in mice.
74 I Annual report 2015 I CIBERER
