Page 96 - CIBERES-2015-eng

Research Groups
Group 33
Programme: Acute Lung Injury / Pneumonia Lead Researcher: Blanch Torra, Lluis
Group members
STAFF MEMBERS: Broceño Corrales, Cristina | Guillamat Prats, Raquel | Montanyà Castells, Jaume | Turón Viñas, Marc.
ASSOCIATED MEMBERS: Artigas Raventos, Antonio | Fernández Fernández, Rafael | Ferrer Roca, Ricard | López Aguilar, Josefina | Martín Loeches Carrondo, Ignacio Esteban | Martínez Pérez, Melcior | Ochagavia Calvo, Ana | Sales López, Bernat | Valles Daunis, Jorge | Villagra García, Ana María
Main lines of research
The main research lines of our group combine preclini- cal and clinical studies from a translational perspective and are focused into two main areas:
• Acute Lung Injury: Early diagnosis, pathophysiology and new therapeutic strategies in acute lung injury (CIBERES Groups 23, 29 and 33)
- Pneumonia: Project of Translational Multidisciplinary Research in Respiratory Tract Infections. (CIBERES Groups 14 and 33).
We are interested in the characterization of molecular, cellular and physiological changes related to the devel- opment of acute lung injury, as well as the impact on other organs or systems and the development of new therapeutic strategies.
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tion (MV). Processing and storing digital signals from monitoring equipment or ventilators. • Software for interpretation, analysis and multimodal-multichannel physiological-diagnosed computerized interpretation of biomedical signals.
Development of experimental models (animals and cell cultures) for the characterization of new mecha- nisms involved in acute lung injury (ALI) and preven- tion strategies. (CIBERES Groups 23, 29 and 33). Development of new therapeutic strategies for ALI and ARDS management: Pharmacological treat- ment (systemic or inhaled) by administering antico- agulants, heparin, AT-III, thrombomodulin in animal and cell culture models. • Cell therapy based on local instillation of mesenquimal stem cells or type II alve- olar cells in animal models of ALI.
clinical and experimental approach of the axis brain- lung during mechanical ventilation (CIBERES Groups 29 and 33; GTC I3A CIBER-BBN and SEPAR): Molec- ular alterations in brain and lung • Characterization
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1. monitoring of critically ill patients: Non-invasive moni- toring • Development of software for continuous mon- itoring of critically ill patients on mechanical ventila-
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