Page 81 - CIBERSAM-2015-eng

Research Groups
Most relevant scientific articles
saMara Mt, leucht c, leeFlanG MM, anGhelescu IG, chunG yc, cresPo-Facorro B et al. Early Improvement As a Predictor of Later Response to Antipsychotics in Schizophrenia: A Diagnostic Test Review.The American journal of psychiatry. 2015;172(7):617-29.
roIz-santIanez r., ortIz-García de la Foz V., ayesa-ar- rIola r., tordesIllas-GutIérrez d., JorGe r., Vare- la-GóMez n. et al. No progression of the alterations in the cortical thickness of individuals with schizophrenia-spec- trum disorder: A three-year longitudinal magnetic reso- nance imaging study of first-episode patients. Psycholog- ical Medicine. 2015;45(13):2861-2871.
BulIk-sullIVan Bk, loh Pr, FInucane hk, rIPke s, yanG J, Schizophrenia Working Group of the Psychiatric Genom-
Highlights
Our research group has continued the progress of several research projects that were initiated in the past two years on non-affective psychosis, neuroim- aging, genomic, pharmacogenomics,... And we also have got funding to carry out new projects:
• Exp.: PIE15/00079. Títle: Personalized medicine in HCV infection: understanding and predicting hepatic and systemic responses in the era of the new antiviral Drugs. Agency: MINECO. Instituto de Salud Carlos III. “AES de Proyectos Integrados de Excelencia 2014” call. (PI: J. Crespo);
• Exp.: SAF2015-71526-REDT. Title: Brain devel- opment and early stressful conditions in mental health: the mediating role of epigenetic mech- anisms and neuroimaging correlates. (PI: L. Fañanas). Call: Acciones de Dinamización de “Re- des de Excelencia” from MINECO Agency;
• Exp.: PIE14/00031. Títle: Understanding Obesity (Ob), Metabolic Syndrome (MetS), Type 2 Diabetes (T2DM) and Fatty Liver Disease (FL): a multidis- ciplinary approach. Agency: MINECO. Instituto de Salud Carlos III. “AES de Proyectos Integrados de Excelencia 2014” call. (PI. J.M. Mato).
ics Consortium et al. LD Score regression distinguishes confounding from polygenicity in genome-wide associa- tion studies.Nature genetics. 2015;47(3):291-5.
hIBar d.P., steIn J.l., renterIa M.e., arIas-Vasquez a., desrIVIeres s., Jahanshad n. et al. Common genetic variants influence human subcortical brain structures. Nature. 2015;520(7546):224-229.
ayesa-arrIola r., alcaraz e.G., hernández B.V., Pérez-IGlesIas r., lóPez MorInIGo J.d., duta r. et al. Su- icidal behaviour in first-episode non-affective psychosis: Specific risk periods and stage-related factors. European Neuropsychopharmacology. 2015;25(12):2278-2288.
It is of note that our group published during 2015 six articles in scientific journals ranked in the first decile in JCR (Web of Science) with an special mention to an article published in Nature describing common genetic variants influence human subcortical brain structures.
As part of our major interest in building up solid re- search and scientific collaborations with interna- tional group, we keep up our active involvement in ENIGMA, ENPACTSZ, PEIC, PGC and also we have es- tablished a new and productive collaboration with the Brain Center Rudolf Magnus (BCRM) at the Universi- ty Medical Center (UMC), Utrecht (The Netherlands), with Prof. Neeltje van Haren and Prof. Dr. René Kahn. Exp.: JC2015-00351. Title: The better understanding of the pathophysiology of neurocognitive deficit in psychotic disorders using neuro-imaging.
We have also applied for a international patent to the OEPM on genomic variations and treatment re- sponse “Método de monitorización de tratamiento antipsicótico” (PCT/ES201/5070608). Inventors: Prof. Jesús Vicente SAINZ MAZA and Prof. Benedic- to Crespo Facorro.
Institution: Instituto de Investigación Marqués de Valdecilla · Contact: Hospital Univ. Marqués de Valdecilla Avda. Valdecilla S/N. 39008 Santander · Tel.: 942 202 545 · E.mail: [email protected]
Website: http://goo.gl/17p3Ug
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