Page 101 - CIBERER2016-ENG

Most relevant scientific articles
• Nozal P., Bernabeu-Herrero M.E., Uzonyi B., Szilagyi A., Hyvarinen S., Prohaszka Z. et al. Heterogeneity but individual constancy of epitopes, isotypes and avidity of factor H autoantibodies in atypical hemolytic uremic syndrome. Molecular Immunology. 2016; 70:47-55.
• Blom A.M., Corvillo F., Magda M., Stasilojc G., Nozal P., Perez-Valdivia M.A. et al. Testing the Activity of Complement Convertases in Serum/Plasma for Diagnosis of C4NeF-Mediated C3 Glomerulonephritis. Journal of Clinical Immunology. 2016;1-11.
• Corvillo F, García-Morato MB, Nozal P, Garrido S, Tortajada A, de Córdoba SR et al. Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy.Clinical and experimental immunology. 2016.
• Zanichelli A., Longhurst H.J., Maurer M., Bouillet L., Aberer W., Fabien V. et al. Misdiagnosis trends in patients with hereditary angioedema from the real-world clinical setting. Annals of Allergy, Asthma and Immunology. 2016;117(4):394-398.
• Longhurst H.J., Aberer W., Bouillet L., Caballero T., Maurer M., Fabien V. et al. The Icatibant Outcome Survey: Treatment of laryngeal angioedema attacks. European Journal of Emergency Medicine. 2016;23(3):224-227.
Hightlights
During 2016, our group has continued developing its main research lines, with financial support from public and private funds. The PI Margarita López Trascasa leads 2 public research projects, SAF2012-38636 (until December 31, 2016) and PI15-00255 (2016-2018), and she has received a grant from the Spanish National Society for Nephrology (SENEFRO) for a novel project on glomerulonephritis and lipodystrophia. Pilar Sánchez-Corral, moreover, is the PI of projects PI12-00597 (until June 31, 2017) and PI16-00763 (2017- 2019), both of them focused on atypical Haemolytic Uraemic Syndrome.
Several group’s members have taken part in scientific meetings on thrombotic microangiopathies and Hereditary Angioedema as guest speakers. Alberto López and Pilar Nozal presented their results in the Spanish Society for Immunology meeting held on May at Alicante, where Fernando Corvillo was awarded with the “Best Poster Prize”.
The book “Angioedema” (ISBN: 978-84-944977-0-4), coordinated by Teresa Caballero (with Alberto López and Margarita López as authors of one chapter), was also presented on May. In September, 2 PhD theses from our group were defended, and obtained the summa cum laude (“Defects in complement Factor H-related proteins in renal pathology” by María Elvira Bernabéu; and “Antibodies against complement alternative pathway proteins in renal disease” by Pilar Nozal).
In November 28, 140 professionals from the National Health system attended the second edition of “Complement in Renal Pathology”, a training course held at Hospital La Paz and funded by CIBERER.
Our group has significantly contributed to the Universidad de Alcalá-specific degree “Especialista en Angiodema Hereditario”, coordinated by Teresa Caballero. Dr. Caballero has also received the IdiPAZ award for her work on Hereditary Angioedema and quality of life. She is PI of several clinical trials, like CSL830- 3002 related with profilaxis with subcutaneous C1-Inhibitor.
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