Page 117 - MemoriaCIBER2019-ENG

CIBERESP 117
Epidemiological Surveillance of Cancer
The Epidemiological Surveillance of Cancer subprogramme, coordinated by Pablo Fernández and Ma José Sánchez, has developed a remote GEO-CIBER application for the geocoding of 9,488 cases of breast, colon-rectum and lung cancer, included in the project “Multilevel Population Study of Socioeconomic Inequalities in the Geographical Distribution of Incidence, Mortality and Net Cancer Survival in Spain”, funded by the ISCIII, and which aims to characterise and eva- luate the impact of socioeconomic inequalities on incidence, excess mortality, premature mortality and net survival for 3 of the cancers with greatest incidence in Spain.
We have worked with the European Deprivation Index and the new Deprivation Index in Spain (2011) by census sec- tion, prepared by the Group of Social Determinants of Health of the Spanish Society of Epidemiology.
In 2019, a collaboration/agreement was established with the AECC to evaluate the website of the AECC Cancer Ob- servatory and a technical report was prepared with proposals for improvement. In addition, 4 scientific articles were produced that are in the process of peer review.
P2. Communicable disease prevention, surveillance and control (PREVICET)
Coordinator: Pere Godoy García
The groups led by Àngela Domínguez and Carmen Muñoz have participated in the project on the evolution of invasive pneumococcal disease after the introduction of the 13-valent pneumococcal conjugate vaccine in the sys- tematic schedule (PI: Juan José García PI17 / 00337).
The groups led by Àngela Domínguez and Cristina Rius have continued with the project to characterise severe ca- ses of influenza (3 articles have been published). In addition, they have collaborated in the project for hospitalised patients with severe and mild flu for the 2017-18 season.
Funding has been obtained for the project “Effectiveness of influenza and pneumococcal vaccination to prevent hospitalisation in people under 65 who are at risk” (PI: Àngela Domínguez PI19 / 00354).
The group led by Amparo Larrauri, together with other PREVICET groups, has participated in the project on the effectiveness of the influenza vaccine (ECDC Call for tender) (two articles in Eurosurveillance). The study “Effecti- veness of the influenza vaccine in pregnant women to prevent serious hospitalized cases in infants younger than six months of age” (groups 1, 11, 13, 32) and another on the impact of influenza vaccination programmes (an article in Eurosurveillance). Vaccine research contributed to reports for the selection of vaccine strains (GIVE 2019, WHO). The concern generated by the measles outbreaks in Europe has been addressed through articles and interviews.
The group led by Juan E. Echevarría, along with other PREVICET groups, has participated in 7 research projects on emerging diseases in Spain. They cover aspects related to the integration of surveillance, including the molecular characterisation of viruses, vaccine effectiveness, possible factors related to vaccine failure, as well as co-evolu- tionary factors of viruses and their related reservoir hosts (bats) related to the emergence of new zoonoses. The results of these projects have led to different collaborative publications as well as participation in articles and interviews in the media.
The group led by Jordi Figuerola, together with other PREVICET groups, have determined that the invasive mosquito Aedes albopictus is a competent vector for the Zika virus and may, therefore, lead to facilitating indigenous trans- mission cycles (Gutiérrez-López et al . 2019). Only 25% of pregnant women infected with Zika virus after traveling to countries at risk presented symptoms of disease and the three cases with problems in fetal development were associated with infections during the first trimester of pregnancy (Sulleiro et al . 2019). Also studied has been how the results of the Zika IgG and Zika IgA tests together with the date of onset of symptoms can help the diagnosis of these infections (Amaro et al. 2019), and the Zika virus infections imported into Spain after international travel have been characterised (Crespillo-Andujar et al. 2019). Finally, how the movement of seagulls can contribute to human exposure to Salmonella, Campylobacter and Chlamydia of zoonotic origin has been modeled (Navarro et al. 2019).