Page 50 - MemoriaDEM-Eng
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RESEARCH GROUPS
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Dyslipidaemia, Inflammation and
PROGRAMME: P1
Endothelial Dysfunction
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Group Members
Lead Researcher
Carmena Rodríguez, Rafael
STAFF MEMBERS
Benito Casado, Esther
óGarca Garca, Ana Brbara
Contact:
Peir Signes, Marta
Instituto de Investigacin Sanitaria INCLIVA
Av. Blasco Ibez, 17. 46010 Valencia ASSOCIATED MEMBERS
Ascaso Gimilio, Juan Francisco
Phone: (+34) 96 386 28 94
E.mail: [email protected] · Website: www.incliva.es
Blesa Lujan, Sebastian
Catal Bauset, Miguel
Martnez Hervas, Sergio
Main lines of research
• Study of genetic variations present in the exome related to development of
type 2 diabetes and its consecuences.
• Study of insulin resistance and diabetes.
• Detection of genetic alterations (mutations or polymorphisms) involved in
the development of complex diseases with high cardiovascular risk focused
on genes related to the mitochondrial respiratory chain, oxidative stress, 13
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lipid metabolism and diabetes.
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• Diagnosis, preventionand treatment of diabetic foot. PO
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• Study of autosomal dominant hypercholesterolemias and familial combi-
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ned hyperlipidemia.
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• Effect of postprandial lipidemia on cardiovascular system, mainly on lipid A
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profile, inflammatory markers and oxidative stress and the response of EM
circulanting cells to stress caused by hyperlipidemia.
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• Genetic factors involved in the regulation of Body Mass Index (BMI), waist B
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circumference and obesity develpment.
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