Page 176 - MemoriaER-Eng

RESEARCH GROUPS

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Group U756
PROGRAMME:
Sensorineural Pathology

Group Members
Lead Researcher

STAFF MEMBERS
Montoliu José, Lluís

Fernndez Lpez, Almudena

Contact:
ASSOCIATED MEMBERS
Cantero Gonzlez, Marta
Centro Nacional de Biotecnología (CNB-CSIC)
C/ Darwin 3, Campus de Cantoblanco. 28049 Madrid Fernndez Punzano, Juliana

Phone: (+34) 91 585 48 44 Martnez Garca, Mnica
E.mail: [email protected] · Website: http://www.cnb.csic.es/~montoliu/
Montalbn Iglesias, Soledad

Muoz Santos, Diego
Snchez Snchez, scar

Seruggia, Davide Main lines of research
Vicente Garca, Cristina

• Animal models of congenital hypopigmentation diseases: oculocutaneous
albinism type I and ocular albinism.

• Animal models of familial Alzheimer’s, APP locus mutations.

• ALBINOCHIP: Design and validation of a new system for the genetic diag-

nosis of all the mutations known associated with any type of albinism.

• New animal model of achromatopsia involved in the cone deficit pheno-

type observed in the commercial albino mice with no blood relations.
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• Optimization of methodologies in animal transgenesis: new methods, 20
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protocols and techniques for more efficient generation, analysis and cryo- R
preservation of animal models.
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• Pre-clinical therapeutic proposals for albinism, use of L-DOPA and ni- L R
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tisinone in mouse models.
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• Mechanism of action of L-DOPA in retinal development in mammals.
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CI

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