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• e r, r e, s-s J, c Mi, D P, c D .. Primary Preven- 
Most relevant struchosalasalVaDóoVasharMorellaet al
tion of Cardiovascular Disease with a Mediterranean Diet.N Engl J Med. 2013 Feb 25;.
scientific 
• Moleres a, caMPión J, MilaGro Fi, Marcos a, caMPoy c, GaraGorri JM et al.. Differential 
articles
DNA methylation patterns between high and low responders to a weight loss in- 
tervention in overweight or obese adolescents: the EVASYON study.FASEB J. 2013 

Jun;27(6):2504-12.

• GalBete c, toleDo e, Martínez-González Ma, Martínez Ja, Guillén-GriMa F, Marti a. Pro12A- 
la variant of the PPARG2 gene increases body mass index: An updated meta-analy- 

sis encompassing 49,092 subjects.Obesity (Silver Spring). 2013 Jul;21(7):1486-95.

• Boqué n, De la iGlesia r, De la Garza al, MilaGro Fi, oliVares M, Bañuelos o et al.. Preven- 
tion of diet-induced obesity by apple polyphenols in Wistar rats through regulation of 

adipocyte gene expression and DNA methylation patterns.Mol Nutr Food Res. 2013 
Aug;57(8):1473-8.

• M Fi, M Ml, D M c, M Ja. Dietary factors, epigenetic modifi- 
ilaGroanseGoeiGuelartínez
cations and obesity outcomes: progresses and perspectives.Mol Aspects Med. 2013 

Jul-Aug;34(4):782-812.



The achievements of this research team are focused on the interactions between 
Highlights
nutrition, obesity and health, with emphasis on those mechanisms involved in the 

influence of energy balance on inflammation , lipid metabolism, adipokines and in- 
tracellular messengers , being this a project partially funded by MINECO .

Also this group has investigated of different molecules and bioactive compounds 

such as fatty acids, resolvins , polyphenols, etc. and its infuence on digestion and 
intestinal absorption , appetite and nutrigenetic / epigenetic processes , in part 

linked to INCOMES project.
Biomarker research related to the diagnosis and evolution of processes related to 

obesity performed by this group have been oriented on the search for nutrige- 

nomics markers ( polymorphisms, gene expression) and epigenetic marks( DNA 
methylation, microRNAs ), being partly funded by the EXPLORE project.

Studies of diet therapy and personalized nutrition have investigated the relations- 

hip of weight loss in obese individuals according to genotype and the treatments of 
the different comorbidities that accompany obesity and metabolic syndrome, some 

of which are integrated in European projects ( PREVIEW AND FOOD4ME ) and na- 
tional ( PREDIMED ).

EUROPEAN PROJECTS LIST 

• FOOD4ME - Personalised nutrition: An integrated analysis of Opportunities and
challenges.

• PREVIEW - Prevention of diabetes a lifestyle intervention and population studies 

in Europe and aroud the World.
13
NATIONAL PROJECTS LIST 0
•  2
Bioactive lipid mediators derived from omega- 3 fatty acids : potential application
RT
in obesity , inflammation and insulin resistance.
PO
E
• EXPLORE - Hypoxia can be both cause and treatment for obesity and its associated  R
AL
diseases?.
U
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• PREDIMED - healthy in the primary prevention of chronic diseases Power.
A
 / 
• INCOMES- Guide for sustaining health claims on food : immune , metabolic BN
syndrome and cognitive function.
O
ER
B
CI

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