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RESEARCH GROUPS
Dyslipidaemia, Inflammation
and Endothelial Dysfunction
Programme: P1
Lead Researcher: Carmena Rodríguez, Rafael Group members
STAFF MEMBERS: Benito Casado, Esther | García García, Ana Bárbara | Peiro Signes, Marta ASSOCIATED MEMBERS: Ascaso Gimilio, Juan Francisco | Blesa Luján, Sebastián | Català Bauset, Miguel |
Chaves Martínez, Felipe Javier | Martínez Hervás, Sergio | Real Collado, José Tomás
Main lines of research
• Study of genetic variations present in the exome related to development of type 2 diabetes and its consecuences .
• Study of insulin resistance and diabetes .
• Detection of genetic alterations (mutations or polymorphisms) involved in the development of com- plex diseases with high cardiovascular risk focused on genes related to the mitochondrial respiratory chain, oxidative stress, lipid metabolism and diabetes .
• Diagnosis, preventionand treatment of diabetic foot .
• Study of autosomal dominant hypercholesterolemias and familial combined hyperlipidemia .
• Effect of postprandial lipidemia on cardiovascular system, mainly on lipid profile, inflammatory mar- kers and oxidative stress and the response of circulanting cells to stress caused by hyperlipidemia .
• Genetic factors involved in the regulation of Body Mass Index (BMI), waist circumference and obesity develpment .
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CIBERDEM » Annual report 2014
