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RESEARCH GROUPS
Diabetes and Metabolism Research Group
Programme: P2 y P4
Lead Researcher: Simó Canonge, Rafael Group members
STAFF MEMBERS: Bogdanov, Patricia Mónica | Corraliza Márquez, Lidia | García Ramírez, Marta | Ramos Pérez, Lorena
ASSOCIATED MEMBERS: Ciudín, Andreea | Enquix Elena, Natalia | Hernández Pascual, Cristina | Lecube Torello, Albert | Martínez Selva, David | Mesa Manteca, Jorge | Sáez López, Cristina | Sola Adell, Cristina | Villena Delgado, Josep Antoni
Main lines of research
• Physiopathology of diabetic retinopathy The main aim of this line of research is to identify new targets for the treatment of diabetic retino- pathy (DR) . In this regard it should be noted that we are coordinating the first clinical trial aimed at testing the effectiveness and safety of neuroprotective agents for the treatment of DR (EudraCT -2012-001200-38) . This project has been funded by EC (EUROCONDOR-HEALTH-2011- FP7-278040) . In addition, is also noteworthy that we are partners of the project “Early Prevention of Diabetes Com- plications in people with hyperglycaemia in Europe” (e-PREDICE . FP7-279074) in which we are the responsible for measuring the biomarkers of DR .
• Insulin resistance and obesity: new pathogenic candidates and the study of co-morbidities . The main objective is to investigate the pathogenic mechanisms of obesity and its co-morbidities and to find out new therapeutic targets . As a result of our recent findings we are giving priority to the role of sex hormone binding globulin (SHBG) and mitochondrial dysfunction in the pathogenesis of obesity, insulin-resistance and type 2 diabetes .
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