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RESEARCH GROUPS
Transcriptional mechanisms
of pancreatic function
Programme: P3
Lead Researcher: Vallejo Fdez. de la Reguera, Mario Group members
STAFF MEMBERS: Fernández Pérez, Antonio | Mirasierra Cuevas, Mercedes ASSOCIATED MEMBERS: Ruiz Cañas, Laura
Main lines of research
• The characterization of phenotypic alterations of pancreatic islets in the absence of the homeoprotein Alx3 .
• The requirement of Alx3 for the maintenance of glucose homeostasis and metabolic activity in vivo .
• The identification of transcriptional targets regulated by Alx3 .
• Alx3 and diabetic pregnancy: the role of Alx3 in the regulation of the development of the neural tube and vulnerability to hyperglycaemic insult in its absence .
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CIBERDEM » Annual report 2014
