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RESEARCH GROUPS
Group 3
Programme: Pneumonia
Lead Researcher: González de la Campa, Adela Group members
STAFF MEMBERS: Tirado Vélez, José Manuel ASSOCIATED MEMBERS: Amblar Esteban, Mónica | Ferrándiz Avellano, María José | Martín Galiano, An-
tonio Javier
Main lines of research
• Molecular basis of antimicrobial action in pathogenic bacteria, mainly in Streptococcus pneumoniaee . • Molecullar studies of the fluoroquinolone targets (DNA gyrase and DNA topoisomerase IV) . • Studies on the organization of the genome in supercoiling domains and their role in global transcription . • Effect of fluoroquinolone treatment in the global transcription .
• Role of the S . pneumoniae small RNAs in gene expression . • Characterization of new antimicrobial targets . • DNA topoisomerase I as a new antibiotic target . • Characterization of new virulence factors .
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CIBERES » Annual report 2014
