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RESEARCH GROUPS
Group 4
Programme: Sleep Apnea-Hypopnea Syndrome (SAHS)/ Lung Cancer
Lead Researcher: González Mangado, Nicolás Group members
STAFF MEMBERS: Fernández Arias, José | Pérez Rial, Sandra ASSOCIATED MEMBERS: Fernández Ormaechea, Itziar | Peces Barba Romero, Germán | Rodríguez Nieto,
María Jesús | Seijo Maceiras, Luis Miguel | Suárez Sipmann, Fernando | Villar Álvarez, Felipe
Main lines of research
• CRP of Sleep Apnea: OSA as a risk factor for cardiovascular morbidity and mortality, OSA as a risk factor for cancer and SAHS in women .
• CRP of cancer: Early detection program in subjects at high risk for emphysema or lung function im- pairment . Risk of each individual as his smoking habit and personal and family history . Influence of associated diseases, especially chronic obstructive pulmonary disease (COPD) and emphysema over the risk of developing lung cancer and its prognosis . Genetic and molecular factors that determine the risk profile of each individual .
• CRP of COPD: Susceptibility to the development of lung injury and its evolution up to present the well established disease in animal models . Identification of the key biomarkers in the development and progression of the disease and its translation to the clinic . Cohorts of COPD patients with early onset and with late-stage severe COPD . New therapeutic targets based on the utilization of growth factors in experimental models of disease and in endoscopic implantation in patients of spirals and valves for the treatment of emphysema .
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CIBERES » Annual report 2014