Page 67 - MEMOCiberes014-ENG

Most relevant scientific articles
• tuSMaN G., GroISMaN I., FIoLo F.e., ScaNdurra a., arca J.M., kruMrIck G. et al . Noninvasive monitoring of lung recruitment maneuvers in morbidly obese patients: The role of pulse oximetry and volumetric capnography . Anesthesia and Analgesia . 2014;118(1):137-144 .
• perez-rIaL S., deL puerto-NeVado L., GIroN-MartINez a., terroN-expoSIto r., dIaz-GIL J.J., GoNzaLez-MaNGado N. et aL. Liver growth factor treatment reverses emphysema previously established in a cigarette smoke exposure mou- se model . American Journal of Physiology - Lung Cellular and Molecular Physiology . 2014;307(9):L718-L726 .
• GIroN-MartINez a., perez-rIaL S., terroN-expoSIto r., dIaz-GIL J.J., GoNzaLez-MaNGado N., peceS-BarBa G. . Proliferative activity of liver growth factor is associated with an improvement of cigarette smoke-induced emphysema in mice . PLoS ONE . 2014;9(11):- .
• de torreS J.p., MarIN J.M., MartINez-GoNzaLez c., de LucaS-raMoS p., MIr-VILadrIch I., coSIo B. et al . Clinical appli- cation of the COPD assessment test: Longitudinal data from the COPD history assessment in Spain (CHAIN) Cohort . Chest . 2014;146(1):111-122 .
• MaSa J.F., duraN-caNtoLLa J., capote F., caBeLLo M., aBad J., GarcIa-rIo F. et al . Effectiveness of home single- channel nasal pressure for sleep apnea diagnosis . Sleep . 2014;37(12):1953-1961B .
Highlights
Institution: Instituto de Investigación Sanitaria - Fundación Jiménez Díaz Contact: Instituto de Investigacion Sanitaria - Fundacion Jiménez Díaz Avda . Reyes Católicos, 2 . Madrid · Phone: (+34) 91 550 49 12 · E .mail: ngonzalez@fjd .es http://www .fjd .es/es/cartera-servicios/especialidades-medicas/neumologia
CURRENT PROJECTS
• PI12 /0133 “Association between sleep-disordered breathing and growth rate of cutaneous melanoma.” Collaborating Investigator: N. González-Mangado. AES 2013-2016 • PI13/01909 “Identification of activity mar- kers since the beginning of COPD in experimental models and therapeutic assessment with growth factor LGF” . Principal Investigator: G. Peces-Barba. AES 2013-2016 • NANOCOPD “Bioorthogonal nanoparticles for COPD Theranostics” . Principal Investigator: G . Peces-Barba . Multidisciplinary collaborative projects CIBERBBN-SEPAR- CIBERES • SEPAR # 39 “Effect of CPAP treatment in women with OSA. Multicenter, randomized, controlled trial.” Collaborating Investigator: N. González-Mangado. Grants for Research SEPAR • SEPAR#139 “Role of the liver growth factor (LGF) like regenerative experimental lung emphysema” . Principal Investigator: S . Pérez-Rial . Grants for Research SEPAR • SEPAR # 250 “Reference values for the parameters of maximum oxygen consump- tion, acidosis threshold, ventilatory reserve and cardiac reserve in the Spanish population of European ancestors (VARCO)”. Collaborating Investigator: M. J. Rodriguez-Nieto. Grants for Research SEPAR • NMD2012 “Iden- tification of novel pathogenic mechanisms, triggered by activation of arginase in patients with stable COPD exacerbated in association with bronchiectasis phase.” Principal Investigator: F. Villar-Alvarez. Neumomadrid • NMD2014 “Evaluation of lung damage caused by the electronic cigarette” . Principal Investigator: N . González- Mangado . Neumomadrid .
HIGHLIGHTS RESULTS
• Lung recruitment in morbidly obese patients could be effectively monitored by combining noninvasive pulse oximetry and VCap. SpO2, the elimination of CO2, and Bohr’s dead space. • Liver Growth Factor (LGF) treatment normalizes the physiological/morphological parameters and levels of various systemic inflammatory biomarkers in a chronic cigarette smoke exposure AKR/J model, which may have important therapeutic im- plications for subjects with stable COPD. • One-year longitudinal data show variability in COPD Assessment Test (CAT) scores among patients with stable COPD similar to modified Medical Research Council (mMRC) scale score, which is the best predictor of 1-year CAT changes. • Effectiveness of home single-channel nasal pressure for sleep apnea diagnosis .
www.ciberes.org 67