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RESEARCH GROUPS
Group 5
Programme: Asthma
Lead Researcher: Picado Vallés, César Group members
STAFF MEMBERS: Planas Cerezales, Lourdes | Vennera Trunzo, María del Carmen .
ASSOCIATED MEMBERS: Alobid, Isam | Fernández Bertolín, Laura | Fuentes Prado, Mireya | Guilemany Tos- te, José María | Martínez Antón, Asunción | Molina Molina, María | Mullol Miret, Joaquim | Muñoz Cano, Rosa | Pérez González, María | Pujols Tarres, Laura | Roca Ferrer, Jordi | Serrano Mollar, Ana María | Valero Santiago, Antonio | Xaubet Mir, Antonio .
Main lines of research
• Study of the links between upper airway diseases (rhinitis, rhinosinusitis and nasal polyps) and lower airway diseases (asthma, chronic obstructive pulmonary disease and bronchiectasis) . Relationship bet- ween chronic rhinosinusitis and asthma severity .
• Study of the alterations in the regulation of glucocorticoid receptor in the reduced response to glu- cocorticoids (glucocorticoid resistance) in inflammatory airway diseases (chronic rhinosinusitis, nasal polyposis and asthma) .
• Study of the role of the cyclooxygenase pathaway of arachidonic acid metabolism in the pathophy- siology of airway inflammation (chronic rhinosinusitis, asthma), and in the airways remodelling and lung fibrosis .
• Study of the mechanisms involved in non-steroidal antiinflammatory drugs intolerance in asthma .
• Severe asthma: study of the efficacy of the new biologic therapies (omalizumab) .
• New therapies: 6 .1 In asthma (agonists of EP2 receptor of prostaglandin E2) . 6 .2 Transplantation of type II alveolar cells in the treatment of lung fibrosis .
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CIBERES » Annual report 2014