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RESEARCH GROUPS
Group 8
Programme: Host-Pathogen Interactions
Lead Researcher: Regueiro Comesaña, Verónica Group members
STAFF MEMBERS: Euba Rementería, Begoña | Martinez Moliner, Verónica ASSOCIATED MEMBERS: Garmendia García, Juncal | Llobet Brossa, Enrique | Moranta Mesquida, David
Main lines of research
The main goal of our group is to study the immune response of hosts to face pathogenic microorganisms, and decipher the molecular mechanisms that regulate the interaction between host and pathogen . Thus, we study host response mechanisms, resistance and evasion systems developed by pathogens .
• Molecular dissection of host cellular systems involved in the immune response to front pathogens . • Analysis of Klebsiella pneumoniae adaptations to survive in the lung . • Analysis of antimicrobial peptide resistance mechanisms . • Molecular mechanisms of bacterial infection associated to COPD exacerbation .
• Identification and preclinical evaluation of novel host-directed therapies to treat respiratory infection by the bacterial pathogen nontypable Haemophilus influenzae .
• Molecular evolution and human host adaptation of the bacterial pathogen nontypable Haemophilus influenzae .
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