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RESEARCH GROUPS
Patología Oxidativa
Programme: P3. Complications of Obesity
Lead Researcher: Sáez Tormo, Guillermo Group Members
STAFF MEMBERS: Tormos Muñoz, María del Carmen ASSOCIATED MEMBERS: Cerdá Mico, Concepción | Iradi Casal, Antonio | Vázquez Prado, Antonio
Main lines of research
• Role of oxidative stress in the pathophysiology of cardiometabolic diseases . Special study of obesity and its cardiovascular and neoplasic complications .
• Identification of p53 dependent signal transduction pathways involved in the repair of oxidative stress- induced genetic alterations . Repair enzyme expression and identification of genetic polymorphisms .
• Validation oxidative metabolites (8-oxodG and F2-Isoprostanes) as clinical markers of cardiovascular and tumor diseases .
106 CIBEROBN » Annual report 2014