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• Study of the physiological mechanisms responsible for the regulation of energy balance in the gas- trointestinal tract . Role of ghrelin nesfatin a-1, gastricendogenous cannabinoid, signaling pathway activated by FNDC5 andmTOR/S6k1 .
• Study of the effect of lactation on metabolism . Study of lipid metabolism in adipose tissue and gas- trointestinal mechanisms .
Most relevant scientific articles
• Fernández-aranda F., sauChelli s., Pastor a., González M.l., de la torre r., Granero r. et al . Moderate- vigorous physical activity across body mass index in females: Moderating effect of endocannabinoids and temperament . PLoS ONE . 2014;9(8) .
• Giustina a., Chanson P., kleinBerG d., Bronstein M.d., CleMMons d.r., kliBanski a. et al . Expert consensus document: A consensus on the medical treatment of acromegaly . Nature Reviews Endocrinology . 2014; 10(4):243-248 .
• Vázquez C., Botella-Carretero j.i., Corella d., Fiol M., laGe M., lurBe e. et al . White fish reduces car- diovascular risk factors in patients with metabolic syndrome: The WISH-CARE study, a multicenter randomized clinical trial . Nutrition, Metabolism and Cardiovascular Diseases . 2014; 24(3):328-335 .
• Pye s.r., huhtanieMi i.t., Finn j.d., lee d.M., o’neill t.w., tajar a. et al . Late-onset hypogonadism and mortality in aging men . Journal of Clinical Endocrinology and Metabolism . 2014; 99(4):1357-1366 .
• Crujeiras a.B., zulet M.a., loPez-leGarrea P., de la iGlesia r., Pardo M., Carreira M.C. et al . Association between circulating irisin levels and the promotion of insulin resistance during the weight mainte- nance period after a dietary weight-lowering program in obese patients . Metabolism: Clinical and Experimental . 2014; 63(4):520-531 .
Highlights
Institution: Servicio Gallego de Salud Contact: Laboratorio Endocrinología Molecular Complejo Hospitalario Universitario Santiago C/ Chopuana S/N . 15706 Santiago de Compostela · Tel .: (+34) 981 955 069 · E .mail: endocrine@usc .es Website: www .ciberobn .es
The group of Molecular Endocrinology in 2014 has published 22 articles with a cumulative impact factor of 77 among which Nature Reviews and Human Reproduction Update . During this period, the group has obtained a national project (ISCIII/AES PI14 /01012) and have established agreements with various companies as well as 3 clinical trials . Noteworthy is the beginning of Hologal project (Holoturias, Nuevo recurso marino de Galicia) is a project funded by FEDER-INNTERCONECTA from Conselleria Innovation and Industry and Centro para el Desarrollo Tecnologico e Industrial (CDTI) – Ministerio de Economia . It aims to find new markets and uses for sea cucumber by the fishing and processing sector in Galicia as a strategy for finding new business solutions .
In 2014 have started new research focused on the search for new effective therapies against obesity based on oral treatments with antioxidants and the use of nanoparticles having obtained very encouraging preliminary results . There have also been significant advances in the project The Obesity Paradox in multiple prevalent diseases: a translational approach whose results will be published in the coming months .
Within the CIBER, Endocrinology group actively participates in several scientific programs and the Fat Bank and during the last year they have obtained obvious progress .
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