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• Molecular basis of sexual dimorphism on the energy metabolism and mitocondrial function; patho- logical implications .
• Nutritional and genetic determinants of the development of different obesity phenotypes; association of these phenotypes with diseases risk and mortality .
3- Nutrition, diet and cancer:
• Pro-oxidant and antioxidant nutritional factors and their influence on carcinogenesis: the role of estrogens .
• Dietary patterns defined a priori and a posteriori and incidence and recurrence of cancer . Most relevant scientific articles
• salas-salVadó j., Bullo M., estruCh r., ros e., CoVas M.-i., iBarrola-jurado n. et al . Prevention of diabetes with mediterranean diets: A subgroup analysis of a randomized trial . Annals of Internal Medicine . 2014;160(1):1-10 .
• Fito M., estruCh r., salas-salVadó j., Martínez-González M.a., aros F., Vila j. et al . Effect of the Medite- rranean diet on heart failure biomarkers: A randomized sample from the PREDIMED trial . European Journal of Heart Failure . 2014; 16(5):543-550 .
• GuasCh-Ferre M., hu F.B., Martínez-González M.a., Fito M., Bullo M., estruCh r. et al . Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study . BMC Medicine . 2014;12(1) .
• Martínez-González M.a., toledo e., aros F., Fiol M., Corella d., salas-salVadó j. et al . Extravirgin olive oil consumption reduces risk of atrial fibrillation: The PREDIMED (Prevención con Dieta Mediterránea) trial . Circulation . 2014;130(1):18-26 .
• roswall n., anGquist l., ahluwalia t.s., roMaGuera d., larsen s.C., osterGaard j.n. et al . Association bet- ween Mediterranean and Nordic diet scores and changes in weight and waist circumference: Influen- ce of FTO and TCF7L2 loci . American Journal of Clinical Nutrition . 2014;100(4):1188-1197 .
Highlights
Institution: Universidad de las Islas Baleares Contact: Facultad de Ciencias de Mallorca . Ctra . de Valldemossa km 7 .5 07122 Palma de Mallorca, Islas Baleares · Teléfono: (+34) 971 172 070 E .mail: miguel .fiol@ssib .es
The most important project that has been developed by this group during 2014 was the start of recruitment of the PREDIMED-PLUS study, which was funded by the ISCIII in the 2014 AES call . The PREDIMED-PLUS project aims to evaluate the effect of intensive intervention based on a low-calorie Mediterranean diet, physical activity and behavioral therapy in cardiovascular disease prevention . From our centre Hospital Son Espases, were have recruited over a hundred participants so far . We have also initiated a series of complementary sub-projects associated with PREDIMED-PLUS study, such as performing densitometry to all patients included in baseline and follow-up visits to determine changes in body composition associated with the intervention . We are also performing echocardiograms to a subsample of patients to study the effect of the intervention on the substrate of atrial fibrillation . Researchers Nephrolithiasis group from the UIB, members of CIBER-OBN, are studying the effect of the intervention PREDIMED-PLUS study on uric acid nephrolithiasis . Finally, note that our group leads the CORE laboratory of electrocardiography in order to process and interpret all the ECG performed in the PREDIMED-PLUS study .
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