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• Beiroa d., iMBernon M., GalleGo r., senra a., herranz d., Villarroya F. et al . GLP-1 agonism stimu- lates brown adipose tissue thermogenesis and browning through hypothalamic AMPK . Diabetes . 2014;63(10):3346-3358 .
• Moreno-naVarrete j.M., noVelle M.G., Catalan V., orteGa F., Moreno M., GoMez-aMBrosi j. et al . Insulin resistance modulates iron-related proteins in adipose tissue . Diabetes Care . 2014;37(4):1092-1100 .
Highlights
Institution: Universidad de Navarra Contact: Clínica Universitaria de Navarra · Avda . Pío XII, 36 . 31008 Pamplona, Navarra Tel .: (+34) 948 255 400 E .mail: gfruhbeck@unav .es http://www .ciberobn .es/index .php?option=com_content&view=article&catid =12:grupos&id=118&Itemid=13
RESEARCH PROJECTS
• Study of the implication of extracellular matrix remodeling of the adipose tissue and liver in the onset of obesity and its comorbidities. FIS-ISCIII_Gómez-Ambrosi • Prospective study of the changes in energy ba- lance after bariatric surgery. FIS_INTRASALUD-ISCIII_Frühbeck • Implication of obesity and type 2 diabetes mellitus in colon cancer development . Gene expression analysis involved in metilation, inflammation and tumoral growth in adipose tissue and peripheral blood. DeptoSalud, GobNav_Catalán • Study of the im- plication of aquaglyceroporins in insulin resistance development. Aging effects. PIUNA, UNAV_Rodríguez • Adipose tissue dysfunctionality studies in cardiometabolic alterations associated to obesity and its influen- ces in aging. CAN_Gómez-Ambrosi • Role of interleukin-32 in the regulation of macrophage polarization in adipose tissue . Involvement in the obesity-associated inflammation and comorbidities . FIS-ISCIII_Catalán • Impact of ghrelin isoforms in the development of obesity-related hypertension. FIS-ISCIII_Rodríguez • DO- RIAN - Developmental Origins of Healthy and Unhealthy Ageing . The role of Maternal Obesity . EU-Project_ Iozzo • SPOTLIGHT – Sustainable Prevention of Obesity Through Integrated Strategies. EU-Project_Brug.
CLINICAL GUIDELINES
• Need for a paradigm shift in adult overweight and obesity management - an EASO position statement on a pressing public health, clinical and scientific challenge in Europe.ObesFacts.2014;7:408-16 • Beyond BMI-phenotyping the obesities.ObesFacts.2014;7:322-8 • Interdisciplinary European guidelines on meta- bolic and bariatricsurgery.RozhlChir.2014;93:366-78 • Obesity: a gateway disease with a rising prevalence. ObesFacts.2014;7 Suppl 2:33-6 • An EASO position statement on multidisciplinary obesity management in adults.ObesFacts.2014;7:96-101 • Interdisciplinary European guidelines on metabolic and bariatric surgery. ObesSurg .2014;24:42-55 .
COLLABORATIONS
• Estancia de formación de Natalia Moreno (Departamento de Biología Celular, Fisiología e Inmunología- IMIBIC,Córdoba), miembro del grupo liderado por Prof . Manolo Tena Sempere (CIBEROBN) .
• NACIONAL: Collaboration&publications with CIBERobn groups of Drs . Casanueva, Fernández- Real, Fernán- dez-Aranda, Diéguez, Tena-Sempere, Botella, Argente, Tinahones Villaroya, Fitó-Colomer, López Miranda .
• INTERNACIONAL: Collaboration & publications with Drs . Pietiläinen (Helsinki,Finland), Calamita (Bari,Italy), Yumuk (Istanbul,Turkey), Toplak (Graz,Austria), Woodward (European Association for the Study of Obe- sity on behalf of the Executive Committee), Halford (Liverpool,UK), Blundell (Leeds,UK), Dulloo (Fribourg, Switzerland), Oppert (Paris, France), Fried (Prague, Czech Republic), Scopinaro (Genoa,Italy), Weiner (Frankfurt,Germany), Yashkov (Moscow,Russia), Maislos (Beer Sheva,Israel) y Acerlus(Leicester,UK) .
AWARDS
• Iberoamerican “Cortes de Cádiz” Award in Surgery _J.Álvarez Cienfuegos. • Medical Senior Fellowship “Colegio Médicos de Navarra” _V.Valentí.
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