Page 93 - MEMOCiberobn014-ENG

• iBero-BaraiBar i., aBete i., naVas-Carretero s., Massis-zaid a., Martínez j.a., zulet M.a. Oxidised LDL levels decreases after the consumption of ready-to-eat meals supplemented with cocoa extract within a hypocaloric diet . Nutrition, Metabolism and Cardiovascular Diseases . 2014;24(4):416-422 .
• Martínez j.a., MilaGro F.i., ClayCoMBe k.j., sChalinske k.l. Epigenetics in adipose tissue, obesity, weight loss, and diabetes . Advances in Nutrition . 2014;5(1):71-81 .
Highlights
Institution: Universidad de Navarra Contact: Universidad De Navarra · Campus Universitario · 31080 Pamplona · Teléfono: 948425600 . 806424 · E .mail: jalfmtz@unav .es
The group’s research has focused on the following scientific areas:
• Nutrition: Studies of the role of macronutrient distribution and the presence of antioxidants within energy-restricted diets on weight loss, inflammation and manifestations of metabolic syndrome .
• Adipobiology: Characterization of various adipokines involving mediators and cell differentiation processes, lipogenesis, lipolysis, etc . in adipocytes .
• Complications of obesity and environmental factors: Investigation of possible relationships bet- ween the processes of weight loss and manifestations related to mood / depression .
• Obesity in childhood and adolescence: Relationships of the influence of the antioxidant capacity of hypocaloric diets on weight loss and inflammation in children and adolescents .
• Biomarkers: Assessment of the role of irisin, ghrelin and vitamin D in energy homeostasis as well as the involvement of telomeres length, SNPs and DNA methylation on epigenetic signatures and metabolomics approaches .
• Pathophysiology: Implications of the physiological situation on obesity in different populations and on the implementation of customized diets depending on the phenotype / genotype .
PROJECTS
• Títle: Nutricion personalizada y biomarcadores nutrigenomicos de la inflamacion asociada a la dieta y la obesidad . Papel de nutrientes, adiposidad y edad (AGL2013-45554-R) . Funding: Ministerio de Economía y Competitividad (Spain) . Duration: 2014-2016 . Principal investigator: Prof . J . Alfredo Mar- tínez/Dr . Fermín Milagro .
• Guide about the Substantiation of Health Claims in Food in the XVI Meeting of the SEÑ – Characterization and stability studies concerning bioactive compounds – Toxicological studies of bioactive compounds – Nutridynamics - mechanisms of action of bioactive compounds in the body
– Selection of relevant biomarkers for nutritional claims – Nutrikinetic and bioavailability of bioactive compounds – Cause-effect relationships in intervention studies with functional foods
www .ciberobn .es 93