Page 71 - MemoriaCIBER-2018ESP

10 publicaciones más relevantes del CIBEREHD durante 2018 según factor de impacto
FI Publicación
Systemic messenger RNA as an etiological treatment for acute intermittent porphyria. Nat Med. 2018 Dec;24(12):1899-1909
Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modelling of Liver Fibrosis. Cell Stem Cell. 2018 Jul 5;23(1):101-113.e7.
Mechanisms of Damage to the Gastrointestinal Tract from Nonsteroidal Anti- Inflammatory Drugs. Gastroenterology. 2018 Feb;154(3):500-514.
Long-term Efficacy and Safety of Stem Cell Therapy (Cx601) for Complex Perianal Fistulas in Patients with Crohn's Disease. Gastroenterology. 2018 Apr;154(5):1334-1342.e4.
Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome. Gastroenterology. 2018 Jul;155(1):168-179.
Fibrosis Severity as a Determinant of Cause-Specific Mortality in Patients with Advanced Non-alcoholic Fatty Liver Disease: A Multi-National Cohort Study. Gastroenterology. 2018 Aug;155(2):443-457.e17
Effects of Prebiotics vs a Diet Low in FODMAPs in Patients with Functional Gut Disorders. Gastroenterology. 2018 Oct;155(4):1004-1007.
Simvastatin Prevents Progression of Acute on Chronic Liver Failure in Rats with Cirrhosis and Portal Hypertension. Gastroenterology. 2018 Nov;155(5):1564-1577
Efficacy and Safety of Budesonide, vs Mesalazine or Placebo, as Induction Therapy for Lymphocytic Colitis. Gastroenterology. 2018 Dec;155(6):1795-1804.e3
Molecular predictors of prevention of recurrence in HCC with sorafenib as adjuvant treatment and prognostic factors in the phase 3 STORM trial. Gut. 2018 Aug 14. pii: gutjnl-2018-316408.
32,6210 23,2900 20,7730 20,7730 20,7730
20,7730
20,7730 20,7730 20,7730
17,0160
Patentes con titularidad CIBER
Solicitadas.
• NUPR1 Inhibition for Treating Cancer. EP18305672.0
EP18382271.7
• Method of Treating Colorectal Cancer. US 16/022597
• Method of Treating Advanced Colorectal Adenoma. US 16/058940
• Human Porphobilinogen Deaminase Derived Proteins and Polynucleotides And Uses Thereof. WO2018/206125A1
• Cepa de Bifidobacterium longum sub infantis y uso de la misma. P201830961
Concedidas.
• Derivados de 4-fenildihidropiridina para el tratamiento y/o prevención de una infección
o enfermedad causada por Helicobacter. P201831019 •
Predictive response biomarkers to corticosteroids. EP17382246.1
In vitro method for identifying colorectal adenomas or colorectal cancer. PCT/ EP2017/080560
“Biomarkers for colorectal cancer”. EP17382267
Biomarkers for colorectal cancer. EP 17382267.7
• Derivados de ácido ursodecoxicólico para el tratamiento de enfermedades hepáticas poliquísticas. PCT/ES2018/070840
• Treatment of fibrosis and inhibition of fibrosis in non-alcoholic fatty liver disease patients. US 16/182767
• Methods for diagnosing and treating acute or chronic liver, kidney or lung disease.
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CIBEREHD | MEMORIA ANUAL 2018