Page 106 - MemoriaOBN-Eng

á
RESEARCH GROUPS

á
í
í
ííó
ñ
á
í
íí
áí
íí
í

á
ó
íí
é

ú

úóó
íí
PROGRAMME:
Obesidad, Neuroendocrinología y
P6. Physiopathology of body
Función Reproductora (UCO)
weight homeostasis

Group Members
Lead Researcher
PROGRAMA:
Tena Sempere, Manuel
STAFF MEMBERS
Grupo 3
Depresin,
éMolero Murillo, Laura
Transtorno bipolar
Moreno Herrera, Antonio
Contact:
Rodrguez Snchez, Ana Belen
Facultad de Medicina. Universidad de Córdoba Snchez-Garrido Nogueras, Miguel A.

Avd. Menndez Pidal s/n. 14004 Córdoba
Phone: (+34) 957 21 82 81 ASSOCIATED MEMBERS
E.mail: [email protected] · Website: www.uco.es
Aguilar Bentez De Lugo, Enrique

Benito Lpez, Pedro
Castao Fuentes, Justo Pastor
Main lines of research
Castellano Rodrguez, Juan Manuel
Daz-Ruz Ruz, Jos Alberto
Our group implements integral analyses of various aspects of the pathophysiology
Fernndez Fernndez, Rafel
of obesity and its complications, by the use of state-of-the-art techniques and ce-
Garca Galiano, David llular and animal models, as well as human samples. Our major research lines are:
Garca Navarro, Mara Socorro
• ADIPOBIOLOGY. We conduct proteomic analyses directed to the identification
Gaytan Luna, Francisco
Leon Tellez, Silvia of novel molecular targets that are altered in the adipose tissue in obesity, with
special interest in the characterization of the differential proteomic profile of
Luque Huertas, Ral M.
Malagn Poyato, Mara Del Mar the various fat depots and their different components (mature adipocytes vs.
stromal-vascular fraction). These studies aim also at the identification of novel
Manferdi Lozano, Mara
molecular markers of adipocyte differentiation and insulin resistance.
Martnez Fuentes, Antonio Jess
Peinado Mena, Juan Ramn • ADIPOSE HORMONE SIGNALING. We aim to characterize the receptors and sig-
naling cascades of key adipokines, with special attention to the characterization
Pineda Reyes, Rafael
Pinilla Jurado, Leonor of the receptors and intracellular signaling of adiponectin.
13
0
Roa Rivas, Juan • NEUROENDOCRINOLOGY OF METABOLIC ALTERATIONS. We aim to characterize 2
Ruz Pino, Francisco the endocrine and metabolic alterations of suitable preclinical models of dere- RT
O
Vzquez Martnez, Rafel Manuel gulated energy balance, with special attention to the analysis of the contribu- EP
Vigo Gago, Eva Mara
tion of somatostatin/cortistatin, ghrelin, GH/IGF-1, insulin, their receptors and R
AL
related molecules, involved in the neuro-hormonal mechanisms responsible for U
the control of food intake, glucose homeostasis and metabolism.
NN
A
• PUBERTY, REPRODUCTION AND OBESITY. We aim to characterize the alterations /
N
of puberty and reproductive function in conditions of energy imbalance, with OB
special attention to the impact of obesity on puberty onset, gonadotropic R
BE
function and fertility. Our interest is also covering the pathophysiology of early CI
onset obesity and its link with pubertal disorders, addressed by the use of sui-
106
table preclinical models.