Page 96 - MemoriaOBN-Eng

RESEARCH GROUPS

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Grupo de Nutrición, Lípidos
PROGRAMME:
P1. Nutrition
y Riesgo Riesgo Cardiovascular

Group Members
Lead Researcher
PROGRAMA:
Grupo 3
Depresin,
Ros Rahola, Emilio
STAFF MEMBERS
Transtorno bipolar
íCofan Pujol, Monserrat
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Sala Vila, Aleix
Contact:
Serra, Mer

Unidad de Lpidos Valls, Cinta
Hospital Clnico y Provincial de Barcelona
ASSOCIATED MEMBERS
C/ Villarroel, 170. 08036 Barcelona · Phone: (+34) 93 227 93 83
E.mail: [email protected]
Alegret Jord, Marta
Laguna Egea, Juan Carlos

Merlos Roca, Manuel
Nuez Lucas, Isabel Main lines of research

Prez Heras, Anna Maria
• Study of variants in genes of lipid metabolism that might illustrate the etiology
Roglans Ribas, Nuria
Snchez Pearroya, Rosa Mara of familial and polygenic hypercholesterolemia and severe hypertriglyceridemia.
•
Ortega, Emilio
Carotid and femoral ultrasound examination. Biomarkers for regular diet.
• Functionality of whole foods and dietary patterns.

• Specific projects within the PREDIMED study, for which the Group directed the

nutritional intervention.

• Randomized controlled trial WAHA (WAlnuts for Healthy Aging): effects of a diet
enriched with walnuts (15% of energy) for 2 y in comparison with a control diet

on age-related cognitive decline and macular degeneration in 700 older persons.
6. Cognitive function evaluated by neuropsychological tests and functional brain
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MRI in familial hypercholesterolemia compared to moderate hypercholesterole- 0
mia and normolipidemia.
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RT
• Cholesterol absorption and synthesis as assessed by determination of plasma O
EP
non-cholesterol sterols by gas chromatography: quantification, genetic deter- R
minants, effect on cardiovascular risk, and associations with lipid responses to AL
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plant sterols, statins, and ezetimibe.
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Influence of long-chain polyunsaturated fatty acids (n-3 from plant and marine /
sources) on carotid atherosclerosis assessed by ultrasound and MRI.
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• Associations of fatty acids profiles in total blood, total plasma and phospholipid R
fractions with cardiometabolic risk factors and non-alcoholic fatty liver; genetic BE
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determinants of the blood omega-3 index; and fatty acid composition of lipid
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rafts and intracellular signal transduction.