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Most relevant scientific articles
• Fernández-millán e., ramos s., álVarez C., BraVo l., GoYa l., martín m.t. Microbial phenolic metabolites im- prove glucose-stimulated insulin secretion and protect pancreatic beta cells against tert-butyl hydrope- roxide-induced toxicity via ERKs and PKC pathways . Food and Chemical Toxicology . 2014;66:245-253 .
• martín m.a., Fernández-millán e., ramos s., BraVo l., GoYa l. Cocoa flavonoid epicatechin protects pan- creatic beta cell viability and function against oxidative stress . Molecular Nutrition and Food Research . 2014;58(3):447-456 .
• de toro-martín J., Fernández-millán e., lizarraGa-mollinedo e., lóPez-oliVa e., serradas P., esCriVá F. et al . Predominant role of GIP in the development of a metabolic syndrome-like phenotype in female wistar rats submitted to forced catch-up growth . Endocrinology . 2014;155(10):3769-3780 .
• moBasHer m.a., de toro-martín J., González-rodríGuez a., ramos s., letziG l.G., James l.P . et al . Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepato- cytes . Journal of Biological Chemistry . 2014;289(42):29406-29419 .
Highlights
FUNDING
• Molecular and cellular mechanisms involved in T2DM and obesity pathogenesis in rats submitted to maternal undernutrition and refed a high fat diet after weaning . MINECO . Ref .BFU 2011-25420 . IP: Carmen Álvarez Escolá . (2012-2015) .
• Study of the mechanisms of insulin resistanceimplication in obesity, diabetes and metabolic syndro- me . (MOIR) . CAM . Ref .P2010/BMD-2423 Programs I+D Biomedicina/2010 . Coordinator Manuel Ros Pérez . URJC . Group Enmeper: IP: Fernando Escrivá Pons .(2012-2015)
CONGRESS
• de toro-martín J, Fernández-millán e, lizárraGa-mollinedo e, esCriVá F, álVarez C. Alpha-cell functionality shows gender-specific adaptations face to a nutritional insult in Wistar rats . Oral Presentation . 50th EASD Annual Meeting . Vienna 15 – 19 September 2014 . Diabetologia 57, S65 .
• Fernández-millán e, de toro-martín J, lizárraGa-mollinedo e, esCriVá F, álVarez C. Defective autophagy results in reduced glycogen breakdown in the liver of IUGR newborn Wistar rats . Consequences for glucose homeostasis . Oral Presentation . 50th EASD Annual Meeting . Vienna 15 – 19 September 2014 . Diabetologia . 57, S107 .
• lizárraGa-mollinedo e, de toro-martín J, Fernández-millán e, GarCía-san Frutos m, Fernández aGulló t, ros m, álVarez C, esCriVá F. Early undernutrition worsens the metabolic effects of high-lipid diets . Poster presentation . 50th EASD Annual Meeting . Vienna 15 – 19 September 2014 . Diabetologia . 57, S299 .
THESIS
• Author:Esther Lizárraga Mollinedo. Director:Fernando Escrivá Pons. · Title: Effects of early undernutrition on the hepatic and cortical insulin sensitivity of suckling rats and metabolic consequences of nutritional rehabilitation in the adult age. · Sobresaliente cum Laude · University Complutense of Madrid · Date: 27/06/2014
• European Doctoral Thesis: Author:Juan de Toro Martín · Directors: Carmen Álvarez Escolá y Elisa Fernán- dez Millán · Title: Nutritional programming of the metabolic síndrome in a model of early undernutrition and later refeeding with a high-fat diet in Wistar rats · Sobresaliente cum Laude. · University Compluten- se of Madrid · Date: 15/12/2014
Institution: Universidad Complutense de Madrid Contact: Facultad de Farmacia . Ciudad Universitaria, S/N . 28040 Madrid . Phone: (+34) 91 394 18 57 · E.mail: [email protected] · Website: http://www.ucm.es/biomol2
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