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RESEARCH GROUPS
Metabolic and Molecular Disturbances
in Diabetes
Programme: P1 y P3
Lead Researcher: Novials Sardà, Anna Maria Group members
STAFF MEMBERS: Alcarraz Vizán, Gema | Brugnara, Laura | Castaño Pérez, Carlos | Murillo García, Serafín
ASSOCIATED MEMBERS: Cadavez Trigo, Lisa | Ceriello, Antonio | García Rovés González, Pablo Miguel | Montane Mogas, Joel | Moreno Asso, Alba | Parrizas Jiménez, Marcelina | Servitja Duque, Joan Marc | Visa Majoral, Montse
Main lines of research
• Mechanisms of pancreatic islet dysfunction in type 2 diabetes mellitus, in particular, the process of cytotoxicity as induced by amyloidogenesis .
• Signalling and transcriptional networks in the pancreatic beta cell, mainly related to the modulation of the transcriptional programme under stress conditions .
• Impact of lifestyle on diabetes: metabolic and molecular responses to exercise and nutrition in diabetic patients and animal models .
• Impact of glucose oscillations on cardiovascular complications of diabetes: mechanisms of endothelial dysfunction .
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