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RESEARCH GROUPS
Investigación y desarrollo en obesidad
y enfermedades asociadas
Programme: P3. Complications of Obesity
Lead Researcher: Tinahones Madueño, Francisco Group Members
STAFF MEMBERS: Coin Arangüez, Leticia | Morcillo Espina, Sonsóles | Oliva Olivera, Wilfredo | Picón César, Inmaculada Concepción
ASSOCIATED MEMBERS: Alcaide Torres, Juan | Barbarroja Puerto, Nuria | Cardona Díaz, Fernando | Cas- tellano Castillo, Daniel | Clemente Postigo, María Mercedes | El Bekay, Rajaa | Fernández García, Diego | Fernández García, José Carlos | García Almeida, José Manuel | García Fuentes, Eduardo | Garrido Sánchez, Lourdes | Gómez Huelgas, Ricardo | López Siguero, Juan Pedro | Macías González, Manuel | Manchas Do- blas, Isabel | Moreno Indias, Isabel | Queipo Ortuño, María Isabel | Roca Rodríguez, María del Mar
Main lines of research
• Microbiota and related diseases . This line is going to study the intestinal bacterial microflora profiles in lean and obese patients with and without insulin resistance to establish the role of this microflora in the origin of obesity and insulin resistance . We have also started a subline that analyzes changes in the microbiota that can cause certain nutrients rich in polyphenols and the relationship of these changes to metabolic diseases .
• Development of metabolic syndrome and lipodystrophy in HIV-infected patients . The aim of this line is to study the possible association of oxidative stress, chronic inflammatory status and antiretroviral therapy with the development of metabolic syndrome (MS) and lipodystrophy (LP) in HIV-infected patients, by analysis of the most relevant blood biomarkers levels .
• Obesity and associated diseases . We study the relationship between obesity and related metabolic diseases . We tried to elucidate the mechanisms that protect certain individuals with obesity to deve- lop metabolic diseases or to develop these much later . Among the diseases associated with obesity, diabetes and postprandial lipemia are two of the areas where we are deepening .
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