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leaD reSearcHer
Dalmau Obrador, Josep
Instituto de Investigaciones Biomédicas August Pi i Sunyer C/ Rosellón, 153, Planta 2 28036 Barcelona
(+34) 93 227 17 38
informacion@ neuroimmunologybcn.org
group website
GROUP MEMBERS
Staff members: Ariño Rodríguez, Helena
Associated members: Armangue Salvador, Thais | Mannara, Francesco | Martínez Hernández, Eugenia | Petit Pedrol, María del Mar | Planaguma Valls, Jesús | Rosenfeld, Myrna | Sabater Baudet, Lidia
Main lines of research
The principal lines of investigation are in the area of translational neuroscience. We aim to identify new disorders, develop biomarkers, and uncover mechanisms of disease in a novel group of neuroinflammatory disorders characterized by highly specific immune responses against neuronal cell surface and synaptic proteins (autoimmune encephalitis).
In addition to the clinical characterization of these disorders, we identify the associated antibody immune responses, develop diagnostic tests, and determine optimal treatment strategies. We are also investigating what leads to the development of the autoimmune response and how the antibodies interfere with neuronal function and cause the disease. These studies include basic laboratory techniques such as immunohistochemistry, immunoblotting and the development of primary neuronal cell culture as well as tissue electrophysiology studies and investigations using advanced microscopy.
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PROGRAMMES
Mitochondrial and Neuromuscular Medicine